Te Xiao1
Waseda University1
Glaucoma is one of the common eye diseases to cause a risk of blindness in severe cases. To prevent the blindness by glaucoma, real-time monitoring of intraocular pressure (IOP) becomes particularly important. The contact lenses built-in IOP sensor can contact continuously with the eye, so they are superior to other IOP measurement system in that it can measure constantly. Many researchers have been working on making wireless smart contact lenses that can detect intraocular pressure. By embedding LCR resonators<sup>[1-2]</sup> in the contact lenses, which can generate changes in inductance, capacitance, or resistance of the pressure sensors., and receiving signals through transmission coils, the purpose of real-time wireless detection of intraocular pressure is achieved. However, the development of smart contact lens remains a challenge, including wireless sensor sensitivity, transparency, durability, and safety.<br/>Here we demonstrate the use of a wireless and highly sensitive IOP monitoring system on pig eyes that is comfortable while wearing. The IOP monitoring system consists of a stretchable gold antenna sensor printed on a moist and soft contact lens for IOP detection. The wireless IOP data reception is made of a reader circuit resonated at 1.39 GHz. We designed a horseshoe-shaped gold antenna, which was then printed on commercially available contact lenses through electrochemical bonding, using poly(3,4-ethylene dioxythiophene) film as an adhesive glue. The printed stretchable IOP sensing lens can be stretched and twisted, which is impossible using a conventional loop antenna<sup>[3]</sup>.<br/><br/><br/>[1] T. Takamatsu, Y. Chen, T. Yoshimasu, M. Nishizawa, T. Miyake, <i>Advanced Materials Technologies </i><b>2019</b>, <i>4</i>, 1800671.<br/>[2] Y. Cui, T. Takamatsu, K. Shimizu and T. Miyake: <i>Applied Physics Express </i><b>2022</b><i>.</i> 15, 20.<br/>[3] Takamatsu, T.; Sijie, Y.; Shujie, F.; Xiaohan, L.; Miyake, T. <i>Multifunctional High Power Sources for Smart Contact Lenses. Adv</i>. Funct. Mater.<b> 2020,</b> 30, 1906225.