Wearable Non-Invasive Biosensors for Health Monitoring at the Molecular Level

The rather reactive and centralized medical approaches in today’s healthcare system prevent individuals from obtaining diagnosis and treatment in a timely and accessible manner. Presently, commercially available devices for remote health monitoring are majorly limited to body’s vitals and glucose levels, limiting access to healthcare. In this talk, I will present the wearable biosensors which utilized sweat to extract individual’s biomolecular information. These sensors integrate flexible electronics and solid-state electrochemical sensors in a single robust platform to achieve reliable analyte quantifications at the site of sweat collection. Specifically, the wearable ultralow-volume sweat sensors make sweat a viable mode of health monitoring at the molecular level across activities, whether active or sedentary, and across user groups, whether young or old, healthy or ill. By using the sensors, continuous sweat analysis can be used to study how the body’s endogenous and stimulated sweating response relates to stress, metabolic conditions, and potentially neurological afflictions through multiplexed quantification of ions, metabolites, and drugs.