Marc Ramuz1,Joseph Troughton1,Pauline Brige2
MINES Saint-Étienne, IMT1,Aix-Marseille Université2
Marc Ramuz1,Joseph Troughton1,Pauline Brige2
MINES Saint-Étienne, IMT1,Aix-Marseille Université2
Pulse oximetry is the most widespread method of monitoring patient heart rate and blood oxygen levels in both clinical and non-clinical settings. These devices tend to be ridged, bulky, and therefore suitable only for short-term use. In addition, they suffer degraded performance due to movement and changes in ambient light levels, and can present variability from one individual to another. To facilitate long-term monitoring of physiological parameters, including heart rate and oxygen saturation, implanted devices are required. Implantation removes interference from external light sources, eliminates sensitivity to skin pigmentation, and allows enhanced performance during movement associated with greater sensitivity.<br/>Here we demonstrate a low cost, ultra-flexible pulse oximetry probe. The hybrid flexible devices are fabricated on 5 µm thick Parylene C using laser ablation to define the circuit design, and integrate a small ridged photodetector and LEDs using a flexible adhesive. Finally, contact between the probe and the processing board is achieved using a flat flexible cable and anisotropic conductive film. Devices are demonstrated <i>in vivo</i> on a sedated porcine subject and calibrated against a standard peripheral SpO<sub>2</sub> meter while the subject’s oxygen intake was varied. In addition to demonstrating the functionality of these implanted devices, we show that the implementation directly on the femoral artery of our devices records a more acute response to the variation in oxygen intake compared to the peripheral measurements.<br/>These devices are low cost and based on biocompatible materials, and can be easily implanted during cardiovascular surgery. This offers a route towards long-term implantation of devices for continuous patient monitoring.