Symposium Z—Thin Films and Surfaces for Bioactivity and Biomedical Applications
Chairs
Cathy Cotell, Naval Research Laboratory
Steven M. Gorbatkin, Oak Ridge National Laboratory
George Grobe, Bausch & Lomb
Anne E. Meyer, State University of New York at Buffalo
Symposium Support
- Oak Ridge National Laboratory
- Howmedica Division of Pfizer
- Physical Electronics Incorporated
*Invited Paper
SESSION Z1: SELF-ASSEMBLY AND POLYMER THIN FILMS
Chair: Steven M. Gorbatkin
Tuesday Morning, November 28
Jefferson (S)
9:15 A.M. *Z1.1
ENGINEERING BIOMATERIALS THAT EXHIBIT RECOGNITION AND SPECIFICITY, Buddy
Ratner, Erika Johnston, Caren Tidwell and Thomas Boland, University of
Washington, Bioengineering and Chemical Engineering, Seattle, WA.
9:45 A.M. Z1.2
PRODUCTION OF A NOVEL SELF-ASSEMBLED, COLLAGENOUS MATRIX MIMICKING THE
HIERARCHICAL STRUCTURE OF NATIVE ALIGNED CONNECTIVE TISSUE, G. Pins, D.
Christiansen and F. Silver, UMDNJ-Robert Wood Johnson Medical School, Division
of Biomaterials, Piscataway, NJ.
10:00 A.M. Z1.3
SELF-ASSEMBLING PEPTIDE MONOLAYERS: ENDOTHELIAL CELL BEHAVIOR ON FUNCTIONALIZED
METAL SUBSTRATES, Elliot L. Chaikof, Hui S. Wang, Theodore M. Winger, Emory
University, Atlanta, GA; Susan Stephens and Richard A. Dluhy, University of
Georgia, Athens, GA.
10:15 A.M. BREAK
10:45 A.M. Z1.4
ELECTRIC FIELD MEDIATED DEPOSITION OF BIOACTIVE POLYPEPTIDES ON NEURAL
PROSTHETIC DEVICES, Christopher J. Buchko, Kenneth M. Kozloff, Atisa Sioshansi,
University of Michigan, Department of Materials Science and Engineering, Ann
Arbor, MI; K. Sue O'Shea, University of Michigan, Department of Cell Biology,
Ann Arbor, MI; and David C. Martin, University of Michigan, Department of
Materials Science and Engineering, Ann Arbor, MI, and Macromolecular Science
and Engineering Center, Ann Arbor, MI.
11:00 A.M. Z1.5
RIPPLE SHAPE, AMPLITUDE AND TEMPERATURE DEPENDENCE IN PHOSPHOLIPID Pß
BILAYERS, Joseph A. Zasadzinski, University of California, Santa Barbara,
Department of Chemical Engineering, Santa Barbara, CA; and J.T. Woodward,
Tulane University, Department of Chemistry, New Orleans, LA.
11:15 A.M. Z1.6
DIRECT OBSERVATION OF THE ROLE OF SP-B IN LUNG SURFACTANT, Michael M. Lipp, Ka
Yee C. Lee, Joseph A. Zasadzinski and Alan J. Waring, University of California,
Department of Chemical Engineering, Santa Barbara, CA.
11:30 A.M. Z1.7
A NOVEL SELF-ASSEMBLED COLLAGENOUS MATRIX WHICH SERVES AS A TEMPLATE FOR
ORIENTED GROWTH OF HYDROXYAPATITE CRYSTAL, D. Christiansen, G. Pins, E. Huang
and F. Silver, UMDNJ-Robert Wood Johnson Medical School, Division of
Biomaterials, Piscataway, NJ.
11:45 A.M. Z1.8
SURFACE INDUCED CALCIUM PHOSPHATE NUCLEATION AND GROWTH, L. Song, A.A.
Campbell, X.S. Li and B.C. Bunker, Pacific Northwest Laboratory, Materials
Science Department, Richland, WA.
SESSION Z2: POLYMERIC AND
CERAMIC SURFACE MODIFICATIONS
Chair: George L. Grobe
Tuesday Afternoon, November 28
Jefferson (S)
1:30 P.M. *Z2.1
PLASMA SURFACE MODIFICATION IN BIOMEDICAL APPLICATIONS, Ih-Houng Loh, Advanced
Surface Technology, Inc., Billerica, MA.
2:00 P.M. Z2.2
POLYSTYRENE SURFACES TERMINATED WITH A SINGLE FUNCTIONALITY OF ALCOHOL, J.Q.
Sun, I. Bello, W.M. Lau, University of Western Ontario, Department of Materials
Engineering, London, Canada; R.H. Lipson, University of Western Ontario,
Department of Chemistry, London, Canada; and Z.D. Lin, Chinese Academy of
Sciences, Institute of Physics, Beijing, China.
2:15 P.M. Z2.3
NEW METHOD FOR BONDING POLY (ETHYLENE OXIDE) PEO TO SURFACES, Susan S. Allgor
and Edward W. Merrill, Massachusetts Institute of Technology, Department of
Chemical Engineering, Cambridge, MA.
2:30 P.M. Z2.4
PULSED LASER DEPOSITION OF COLLAGEN THIN FILMS, J.A. Conklin and C.M. Cotell,
Naval Research Laboratory, Washington, DC.
2:45 P.M. Z2.5
STUDIES OF STRUCTURE AND REACTIVITY OF POLYGLYCOLIC ACID SURFACES: EFFECT OF
THE ALIPHATIC CAPPING GROUP, T.G. Vargo, Geo-Centers, Inc., Fort Washington,
DC; A.S. Rudolph, M.A. Testoff, B.J. Spargo, Naval Research Laboratory, Center
for Biomolecular Science and Engineering, Washington, DC; and C.C. Chu, Cornell
University, Department of Textiles and Apparel, Ithaca, NY.
3:00 P.M. BREAK
3:30 P.M. Z2.6
A DUAL CONSTANT COMPOSITION STUDY OF THE KINETICS OF MINERALIZATION AND
DEMINERALIZATION OF BONE SUBSTITUTES, B.E. Tucker, G.L. Daubendiek,. G.H.
Nancollas, State University of New York at Buffalo, Department of Chemistry,
Buffalo, NY; and J.A. Bearcroft, Smith & Nephew Richards Inc., Memphis,
TN.
3:45 P.M. Z2.7
FORMATION OF TITANIUM DIOXIDE CONTAINING CALCIUM PHOSPHATE CRYSTALLITES: A NEW
PROCESS, Laurent-Dominique Piveteau, Louis Schlapbach, Université de
Fribourg, Institut de Physique, Fribourg, Switzerland; and Beat Gasser, Dr.
h.c. Robert Mathys Foundation, Bettlach, Switzerland.
4:00 P.M. Z2.8
ANALYSIS OF OXYAPATITE IN PLASMA SPRAYED HYDROXYAPATITE COATINGS, K.A. Gross,
C.C. Berndt, P. Stephens and R. Dinnebier, State University of New York at
Stony Brook, Department of Materials Science and Engineering, Stony Brook,
NY.
4:15 P.M. Z2.9
THIN FILM PHOSPHATE BASED BIOACTIVE SUBSTRATES, S. Langstaff, M. Sayer, L.
Weaver, Queen's University, Department of Physics, Kingston, Canada; T. Smith
and S. Pugh, Millenium Biologix, Kingston, Canada.
4:30 P.M. Z2.10
FORMATION AND CHARACTERIZATION OF HYDROXYAPATITE BY WET CHEMICAL METHODS, K.
Panduranga Rao, Central Leather Research Institute, Biomaterials Division,
Madras, India; T.S. Sampath Kumar, C.S. Pal, M. Lata and M. Sivakumar,
University of Madras, Department of Nuclear Physics and Materials Science
Centre, Madras, India.
4:45 P.M. Z2.11
FLUORINE AND FERRIC IONS INCORPORATION IN HYDROXYAPATITE VIA BRUSHITE
HYDROLYSIS METHOD, T.S. Sampath Kumar, M. Lata, C.S. Pal, M. Sivakumar,
University of Madras, Department of Nuclear Physics and Materials Science
Centre, Madras, India; and K. Panduranga Rao, Central Leather Research
Institute, Biomaterials Division, Madras, India.
SESSION Z3: BIOMEDICAL AND BIOSENSOR APPLICATIONS
Chairs: Catherine M. Cotell and Jeanine A. Conklin
Wednesday Morning, November 29
Jefferson (S)
8:30 A.M. *Z3.1
NOVEL POLYMERS FOR BIOMEDICAL APPLICATIONS, Robert Langer, Massachusetts
Institute of Technology, Cambridge, MA.
9:00 A.M. Z3.2
ESCA DETECTION OF SURFACE CARBOXYL GROUP CONCENTRATION OF POLYANHYDRIDES, J.
Chen, J.A. Gardella Jr., SUNY at Buffalo, Department of Chemistry, Buffalo, NY;
E. Mathiowitz and C.A. Santos, Brown University, Department of Molecular
Pharmacology and Biotechnology, Providence, RI.
9:15 A.M. Z3.3
SILICON NANOTECHNOLOGY FOR BIOFILTRATION AND IMMUNOISOLATED CELL XENOGRAFTS, M.
Ferrari W.H. Chu, T. Desai, D. Hansford and M. Zhang, University of California,
Berkeley, Biomedical Microdevices Workshop, Berkeley, CA.
9:30 A.M. Z3.4
A CARBON BASED DRUG DELIVERY SYSTEM FOR LITHIUM, H. Maleki, D. Ila, G.M.
Jenkins and L.R. Holland, Alabama A&M University, Center for Irradiation of
Materials, Normal, AL.
9:45 A.M. Z3.5
ANTIBACTERIAL PROPERTIES OF A SILVER ION CHELATE, A. Razavi, K. Pidcock, A.
Kibbe, A. Fazzi, M. Bradshaw, T. Murray, F. Natitus, J. Site and P. VanFossen,
Wilkes University, Department of Engineering, Wilkes Barre, PA.
10:00 A.M. BREAK
10:30 A.M. *Z3.6
FUNCTIONALIZED FLUOROPOLYMER SURFACES FOR BIOMEDICAL APPLICATIONS, Terrence G.
Vargo, Geo-Centers, Inc., Fort Washington, DC.
11:00 A.M. Z3.7
POLYPYRROLE - A POTENTIAL CANDIDATE FOR STIMULATED NERVE REGENERATION, V.R.
Shastri, C.E. Schmidt, Massachusetts Institute of Technology, Department of
Chemical Engineering, Cambridge, MA; T.-H. Kim, J.P. Vacanti, Harvard
University, Children's Hospital, Department of Surgery, Boston, MA; and R.
Langer, Massachusetts Institute of Technology, Department of Chemical
Engineering, Cambridge, MA and Harvard University, Children's Hospital,
Department of Surgery, Boston, MA.
11:15 A.M. Z3.8
MOLECULAR IMPRINTING OF FILMS OF ACRYLIC POLYMERS, Sajiv Boggavarapu and Paul
Calvert, University of Arizona, Tucson, AZ.
11:30 A.M. Z3.9
NEW STRATEGIES FOR THE FABRICATION OF ENZYME ELECTRODES, K. Shridhara Alva,
L.A. Samuelson, J. Kumar, University of Massachusetts Lowell, Department of
Physics, Lowell, MA; K.A. Marx, University of Massachusetts Lowell, Department
of Chemistry, Lowell, MA; D.L. Kaplan, US Army Natick, Biotechnology Division,
RD&E Center, Natick, MA; and S.K. Tripathy, University of Massachusetts
Lowell, Department of Chemistry, Lowell, MA.
11:45 A.M. Z3.10
MULTILAYER ENZYME ASSEMBLY FOR THE DEVELOPMENT OF A NOVEL FIBER OPTIC
BIOSENSOR, Zhongping Chen, University of Massachusetts Lowell, Department of
Chemistry, Lowell, MA and U.S. Army Natick RD&E Center, Biotechnology
Division, Natick, MA; Harry H. Gao, Jayant Kumar, University of Massachusetts,
Center for Advanced Materials, Department of Physics, Lowell, MA; Kenneth Marx,
Sukant K. Tripathy, University of Massachusetts Lowell, Center for Advanced
Materials, Department of Chemistry, Lowell, MA; and David L. Kaplan, U.S. Army
Natick RD&E Center, Biotechnology Division, Natick, MA.
SESSION Z4: BIOLOGICAL RESPONSE TO
SURFACE-MODIFIED MATERIALS
Chair: Anne E. Meyer
Wednesday Afternoon, November 29
Jefferson (S)
1:30 P.M. Z4.1
CELLULAR RESPONSE TO HETEROGENEOUSLY CHARGED POLYSTYRENE, Ravi Kapur and
Jonathan Black, Clemson University, Clemson, SC; and Grace Picciolo, Food and
Drug Administration, Division of Mechanics and Materials Science, Rockville,
MD.
1:45 P.M. Z4.2
EFFECTS OF ELECTRIC FIELDS ON GROWTH AND PROTEIN SYNTHESIS OF BONE AND NERVE
CELLS IN VITRO, Q. Qiu, M. Sayer, Queen's University, Department of Physics,
Kingston, Canada; M. Kawaja, Queen's University, Department of Anatomy and Cell
Biology, Kingston, Canada; X. Shen and J.E. Davies, University of Toronto,
Center for Biomaterials, Toronto, Canada.
2:00 P.M. Z4.3
HYDROPHILIC SURFACE MODIFICATION OF PROSTHETIC ARTERIAL GRAFTS, J.M. Seeger, J.
Albright, N.V. Klingman, D. Amery, C. Widenhouse, P. Martin and E.P. Goldberg,
University of Florida, Gainesville, FL.
2:15 P.M. Z4.4
CONDITIONS WHICH PROMOTE SELECT CELLULAR FUNCTIONS ON PEPTIDE-MODIFIED
SUBSTRATES, K.C. Dee, Rensselaer Polytechnic Institute, Department of
Biomedical Engineering, Troy, NY; T.T. Andersen, Albany Medical College,
Department of Biochemistry and Molecular Biology, Albany, NY; and R. Bizios,
Rensselaer Polytechnic Institute, Department of Biomedical Engineering, Troy,
NY.
2:30 P.M. *Z4.5
EFFECTS OF CERAMIC TOPOGRAPHY ON BONE HEALING, D.M. Dziedzic, J.E. Davies,
University of Toronto, Centre for Biomaterials, Toronto, Canada; and I.H.
Arita, McMaster University, Department of Materials Science and Engineering,
Hamilton, Canada.
3:00 P.M. BREAK
3:30 P.M. Z4.6
OSTEOBLAST-LIKE CELL ADHESION, MIGRATION AND MINERALIZED MATRIX FORMATION ON
POROUS POLYMER-CERAMIC SYSTEMS FOR BONE REGENERATION, Cato T. Laurencin,
Mohamed A. Attawia and Kelly M. Herbert, The Medical College of Pennsylvania
and Hahnemann University, Department of Orthopaedic Surgery, Philadelphia,
PA.
3:45 P.M. Z4.7
CHARACTERIZATION OF MINERAL DEPOSITS ON PLASMA-SPRAYED HA-COATED Ti-6Al-4V, V.
Benezra, Massachusetts Institute of Technology, Department of Materials Science
and Engineering, Cambridge, MA; M. Spector, Brigham and Women's Hospital,
Department of Orthopedic Research, Boston, MA; and L.W. Hobbs, Massachusetts
Institute of Technology, Department of Materials Science and Engineering,
Cambridge, MA.
4:00 P.M. Z4.8
IN VIVO EVALUATION OF PULSED LASER DEPOSITED HYDROXYAPATITE COATING FOR
PROSTHESIS-BONE BONDING, C.M. Cotell, J.A. Conklin, Naval Research Laboratory,
Washington, DC; R.C.Y. Auyeung, Sachs Freeman Associates, Landover, MD; S.S.
Wong, California Institute of Technology, Pasadena, CA; M. Spector, Brigham and
Women's Hospital, Orthopedic Research, Boston, MA; and G.H. Nancollas, Naval
Research Laboratory, Washington, DC.
4:15 P.M. Z4.9
BIOACTIVE VOID METAL COMPOSITES FOR ORTHOPEDIC IMPLANT DEVICES, Allison A.
Campbell, Gordon L. Graff, Lin Song and Ken R. Sump, Pacific Northwest
Laboratory, Materials Sciences Department, Richland, WA.
4:30 P.M. Z4.10
XPS STUDIES OF THE INTERACTIONS OF BIOCELLS WITH VARIOUS SILICON BASED
SURFACES, S. Seal, University of Wisconsin, Milwaukee, Department of Materials
and LSS, Milwaukee, WI; S. Krezoski, T.L. Barr and D.H. Petering, University of
Wisconsin, Milwaukee, Department of Chemistry, Milwaukee, WI.
4:45 P.M. Z4.11
LASER DEPOSITION OF APATITE BASE BIOCOMPATIBLE CERAMICS, E.N. Antonov, B.N.
Bagratashvili, V.K. Popov, E.N. Sobol, Russian Academy of Sciences, Scientific
Research Center for Technological Lasers, Moscow, Russia; S. Howdle, K. Parker
and T. Parker, University of Nottingham, Nottingham, United Kingdom.
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