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2014 MRS Spring Meeting Logo2014 MRS Spring Meeting & Exhibit

April 21-25, 2014 | San Francisco
Meeting Chairs: Jose A. Garrido, Sergei V. Kalinin, Edson R. Leite, David Parrillo, Molly Stevens


Symposium Y : Biomaterials for Biomolecule Delivery and Understanding Cell-Niche Interactions

2014-04-22   Show All Abstracts

Symposium Organizers

Fan Yang, Stanford University School of Medicine
Wendy Liu, University of California, Irvine
Jordan J. Green, Johns Hopkins University
Ying Luo, Peking University

Symposium Support

Aldrich Materials Science
Grandhope Biotech Co. Ltd.
Y3: Engineering Cancer Niche
Session Chairs
Fan Yang
Tuesday PM, April 22, 2014
Moscone West, Level 2, Room 2004

2:30 AM - *Y3.01
Modeling Normal Mammary Gland to Understand Organ-Specificity and Breast Cancer: The Yin and Yang of the ECM- Nucleus Interactions

Mina J. Bissell 1

1Lawrence Berkeley Laboratory Berkeley USA

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3:00 AM - Y3.02
Deciphering Glioblastoma Cell-Niche Interactions in 3D Using Biomimetic Hydrogels With Decoupled Biochemical and Mechanical Properties

Christine Wang 1 Xinming Tong 2 Fan Yang 1 2

1Stanford University Stanford USA2Stanford University Stanford USA

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3:15 AM - Y3.03
Dorsal Adhesion Slows Glioblastoma Migration in Perivascular Mimics

Andrew Rape 1 Sanjay Kumar 1

1University of California - Berkeley Berkeley USA

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3:30 AM - Y3.04
The Role of Extracellular Matrix Biophysical Properties on Human Glioblastoma Cell Malignancy

Sara Pedron 1 Eftalda Becka 1 Jann N. Sarkaria 3 Mark A. Schroeder 3 Brendan A Harley 2 1

1University of Illinois at Urbana-Champaign Urbana USA2University of Illinois at Urbana-Champaign Urbana USA3Mayo Clinic Rochester USA

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3:45 AM - Y3.05
Gold Hemisphere Nanoparticles for Chemo-Photothermal Treatments of Multidrug Resistance in Cancer

Hyung Joon Kim 1 Sun-Mi Lee 1 Sook Young Kim 2 Min-Kyung Kwon 2 Sol Kim 2 Arthur Cho 3 Mijin Yun 3 Jeon-Soo Shin 2 Kyung-Hwa Yoo 4 1

1Yonsei University Seoul Republic of Korea2Yonsei University Seoul Republic of Korea3Yonsei University Seoul Republic of Korea4Yonsei University Seoul Republic of Korea

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4:00 AM - Y3
BREAK

Y4: Biomaterials for Modulating Immune Responses
Session Chairs
Wendy Liu
Tuesday PM, April 22, 2014
Moscone West, Level 2, Room 2004

4:30 AM - *Y4.01
Clinical HA Biomaterials for Cell Therapy: From Bench to Business

Glenn Prestwich 1

1University of Utah Salt Lake City USA

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5:00 AM - Y4.02
Covalently Coupled Immunostimulant Heterodimers

Rock Mancini 1 Janine Tom 1 Aaron Esser-Kahn 1

1University of California, Irvine Irvine USA

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5:15 AM - Y4.03
Nanoscale Artificial Immune Synapses Used to Controllably Activate T Cells and NK Cells

Derfogail Delcassian 1 David Depoil 3 Dominika Rudnicka 2 Mengling Liu 4 Daniel M. Davis 2 6 Michael L. Dustin 3 5 Iain E. Dunlop 1

1Imperial College London London United Kingdom2Imperial College London London United Kingdom3NYU School of Medicine New York USA4NYU School of Medicine New York USA5University of Oxford Oxford United Kingdom6University of Manchester Manchester United Kingdom

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5:30 AM - Y4.04
Development of Photo-Caged Agonists for Probing Synergies in Immune Cell Activation

Lalisa Stutts 1 Aaron P. Esser-Kahn 1

1UC Irvine Irvine USA

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Y5: Poster Session I
Session Chairs
Tuesday PM, April 22, 2014
Marriott Marquis, Yerba Buena Level, Salons 8-9

9:00 AM - Y5.01
Bioactive Microcapsules as Novel Scaffolds for Cell Therapies

Faifan Tantakitti 1 Shantanu Sur 2 Daniel Carvajal 1 R. Helen Zha 1 Nicholas Stephanopoulos 2 Samuel I. Stupp 1 2 3

1Northwestern University Evanston USA2Northwestern University Chicago USA3Northwestern University Evanston USA

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9:00 AM - Y5.02
Porous Microsphere-Scaffold for Chronic Wound Treatment

Hanif Ghanbar 1 Mohan Edirisinghe 1 Richard Day 1

1University College London London United Kingdom

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9:00 AM - Y5.03
Spiky Nanoparticles for Intracellular Drug Delivery

Xi Xie 1 Alexander Xu 1 Yuhong Cao 1 Nicholas Melosh 1

1Stanford University Stanford USA

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9:00 AM - Y5.05
Multi-Functional Mesoporous Silica Nanoparticles for pH-Responsive Targeted Drug Delivery

Stefan Niedermayer 1 2 3 Veronika Weiss 1 2 3 Annika Herrmann 4 2 3 Alexandra Schmidt 1 2 3 Daniel Edinger 4 2 3 Ernst Wagner 4 2 3 Thomas Bein 1 2 3 Christoph Braeuchle 1 2 3

1LMU Munich Munich Germany2Center for NanoScience (CeNS) Munich Germany3Nanosystems Initiative Munich (NIM) Munich Germany4LMU Munich Munich Germany

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9:00 AM - Y5.06
Gelatin Based Injectable Hydrogel for Islet Cell Carrier

Seung Yong Lee 1 Muhammad Rezwanul Haque 2 Youngro Byun 2 Cheol-Hee Ahn 1

1Seoul National University Seoul Republic of Korea2Seoul National University Seoul Republic of Korea

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9:00 AM - Y5.07
Mesoporous Oxide Nanoparticles for Controlled Release and Targeted Delivery of Antigens

Caroline Bouvie 1 Katharine Epler 1 2 David Padilla 3 Andrew Gomez 2 3 Marissa Anderson 1 4 Patrick Fleig 4 Bryce Chackerian 5 Jeffrey Brinker 1 5 6 Carlee Ashley 2 Eric Carnes 4

1University of New Mexico Albuquerque USA2Sandia National Laboratories Albuquerque USA3University of New Mexico Albuquerque USA4Sandia National Laboratories Albuquerque USA5University of New Mexico Albuquerque USA6Sandia National Laboratories Albuquerque USA

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9:00 AM - Y5.08
A Micropatterned Nanowire Scaffold for the Directed Patterning of Neural Stem Cells with Differentiation to Multiple Cell Types

Cade Fox 1 Jean Kim 2 Hariharasudhan Chirra 1 Tejal Desai 1 2

1University of California, San Francisco San Francisco USA2University of California San Francisco USA

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9:00 AM - Y5.09
Effects of the Non-Thermal Dielectric Barrier Discharge Plasma on Keloid-Derived Stem Cells

Hyojung Kim 1 Ihn Han 2 Kyung Sook Kim 2 Cheol Eui Lee 1

1Department of Physics and Institute for Nano Science, Korea University, Seoul 136-713, Korea Seoul Republic of Korea2Department of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul, Korea Seoul Republic of Korea

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9:00 AM - Y5.10
The Effects of Soluble Factors and Oxygen Tension on Chondrocyte-Stem Cell Interactions and Cartilage Formation

Janice Lai 1 Stephanie Yu 2 Shaheen Jeeawoody 3 R Lane Smith 4 William Maloney 4 Fan Yang 3 4

1Stanford University Stanford USA2Stanford University Stanford USA3Stanford University Stanford USA4Stanford School of Medicine Stanford USA

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9:00 AM - Y5.11
Functionalized Mesoporous Silica Nanoparticles with Mucoadhesive and Sustained Drug Release Properties for Potential Bladder Cancer Therapy

KoonGee Neoh 1 Quan Zhang 1 En-Tang Kang 1 Edmund Chiong 2

1National University of Singapore Singapore Singapore2National University of Singapore Singapore Singapore

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9:00 AM - Y5.12
Sonosensitive Materials: Role of Lipid Polymorphism

Minjee Kang 1 Grace Huang 1 Cecilia Leal 1

1University of Illinois at Urbana-Champaign URBANA USA

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9:00 AM - Y5.13
Effect of the Hydrophobic Modification on the Physico-Chemical Properties of Self-Assembled Glycol Chitosan Nanoparticles for Tumor-Specific Drug Delivery

Giulia Suarato 1 Yizhi Meng 1 2

1Stony Brook University Stony Brook USA2Stony Brook University Stony Brook USA

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9:00 AM - Y5.14
Magnetically Triggered Release of Bioactive Compounds from Magnetic Nanoparticle-Vesicle Aggregates

Andrew Booth 1 2 3 Felicity de Cogan 4 Simon J Webb 1 3 Julie E Gough 2

1University of Manchester Manchester United Kingdom2University of Manchester Manchester United Kingdom3University of Manchester Manchester United Kingdom4University of Birmingham Birmingham United Kingdom

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9:00 AM - Y5.18
An Analytic Toolbox for Simulated Filament Networks

Ronald J Pandolfi 1 Linda S Hirst 1 Lauren Edwards 1

1University of California, Merced Merced USA

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9:00 AM - Y5.19
Nano-Fibrous Scaffolds Provide Niche to Potentiate the Anti-Inflammatory and Angiogenic Paracrine Function of Adipose-Derived Stem Cells

Ni Su 1 Yi Zhong 1 Kai Wang 1 Ying Luo 1

1Peking University Beijing China

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Y1: Biomaterials for Tissue Regeneration
Session Chairs
Jordan J. Green
Tuesday AM, April 22, 2014
Moscone West, Level 2, Room 2004

9:30 AM - *Y1.01
Molecular Elucidation and Engineering of the Stem Cell Fate Decisions

David Schaffer 1 2 3

1University of California Berkeley USA2University of California Berkeley USA3University of California Berkeley USA

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10:00 AM - Y1.02
Encapsulated Adipose-Derived Stem Cell Spheroids Promote Neovascularization and Biocompatibility of Immunoisolation Devices In-Vitro and In-Vivo

Kai Wang 1 Ying Luo 1

1Peking university Beijing China

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10:15 AM - Y1.03
Enhanced Cartilage Formation In-Vivo via Harnessing the Interplay Between Neonatal Chondrocytes and Stem Cells

Janice Lai 1 Stephanie Yu 2 Shaheen Jeeawoody 3 Fan Yang 3 4

1Stanford University Stanford USA2Stanford University Stanford USA3Stanford University Stanford USA4Stanford School of Medicine Stanford USA

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10:30 AM - Y1.04
Biomimetic Patterned Biochemical and Biophysical Properties within Electrospun Nanofibrous Hydrogels

Ryan Wade 1 William Gramlich 2 Ethan Bassin 3 Jason A. Burdick 1 3

1University of Pennsylvania Philadelphia USA2University of Maine Orono USA3University of Pennsylvania Philadelphia USA

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10:45 AM - Y1.05
Tuning the Physicochemical Properties of Artificial Scaffolds to Direct the 3D Self-Organization and Structure Formation of Human Glandular Epithelial Cells

Alec Cerchiari 1 James Garbe 2 Matthew Thomson 3 Michael Todhunter 3 Noel Jee 3 Kyle Broaders 3 Donna Peehl 4 Mark LaBarge 2 Tejal Desai 3 1 Zev Gartner 3 1

1UC Berkeley - UCSF San Francisco USA2Lawrence Berkeley National Laboratory Berkeley USA3UCSF San Francisco USA4Stanford University Palo Alto USA

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11:00 AM - Y1
BREAK

Y2: Modulating Stem Cell-niche Interactions
Session Chairs
Fan Yang
Tuesday AM, April 22, 2014
Moscone West, Level 2, Room 2004

11:30 AM - *Y2.01
Engineering Biochemical and Biomechanical Signals in Hydrogels to Modulate Stem Cell Niche Interactions

Jason Burdick 1

1University of Pennsylvania Philadelphia USA

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12:00 PM - Y2.02
Effect of Substrate Chemistry and Toughness on Proliferation and Differentiation of Human Bone Marrow Stem Cell

Sisi Qin 1 Liudi Zhang 1 Chungchueh Chang 3 Yupo Ma 2 Miriam Rafailovich 1 Jerell Aguila 2

1Stony Brook University Stony Brook USA2Stony Brook University Stony Brook USA3Stony Brook University STONY BROOK USA

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12:15 PM - Y2.03
Matrix Stiffness Regulates PSC differentiation towards Smooth Muscle Cell Lineage

Soah Lee 1 Erica Anderson 2 Xinming Tong 4 Prachi Wani 2 Smruti Phadnis 2 Renee Reijo Pera 2 Fan Yang 3 4

1Stanford University Stanford USA2Stanford University Stanford USA3Stanford University Stanford USA4Stanford University Stanford USA

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12:30 PM - Y2.04
Adhesive Dendrimeric Nano-Conjugates Show Valency-Dependent Properties to Regulate the Viability and Function of Adipose-Derived Stem Cells

Liyang Jiang 1 Caijia Jiang 1 Ying Luo 1

1Peking university Beijing China

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2014-04-23   Show All Abstracts

Symposium Organizers

Fan Yang, Stanford University School of Medicine
Wendy Liu, University of California, Irvine
Jordan J. Green, Johns Hopkins University
Ying Luo, Peking University

Symposium Support

Aldrich Materials Science
Grandhope Biotech Co. Ltd.
Y7: Biomaterials for Drug Delivery II
Session Chairs
Wendy Liu
Ying Luo
Wednesday PM, April 23, 2014
Moscone West, Level 2, Room 2004

2:30 AM - *Y7.01
Shape and Morphology-Induced Effects in Nanoparticle-Mediated Drug Delivery

Samir Mitragotri 1 2

1UCSB Santa Barbara USA2UCSB Santa Barbara USA

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3:00 AM - Y7.02
Targeted Magnetic Nanoparticles for Remote Manipulation of Protein Aggregation

Colleen Loynachan 1 Michael G. Christiansen 1 Ritchie Chen 1 Mila'na Jones 3 Polina Anikeeva 1 2

1Massachusetts Institute of Technology Cambridge USA2Massachusetts Institute of Technology Cambridge USA3Massachusetts Institute of Technology Cambridge USA

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3:15 AM - Y7.03
Nanotopographical Cues Enable Delivery of High Molecular Weight Therapeutics Across Epithelium

Laura Aiko Walsh 1 Suzanne Bock 2 4 Michael Koval 3 Russell Ross 4 Tejal Desai 1

1UC Berkeley/UCSF San Francisco USA2Georgia Institute of Technology Atlanta USA3Emory University School of Medicine Atlanta USA4Kimberly-Clark Corporation Roswell USA

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3:30 AM - Y7.04
Peptide Discovery to Target Cancerous Collagen for Cancer Nanomedicine

Hyo-Eon Jin 1 2 Seung-Wuk Lee 1 2

1University of California, Berkeley Berkeley USA2Lawrence Berkeley National Laboratory Berkeley USA

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3:45 AM - Y7.05
Targeted Delivery of Antibiotics to Cells Infected with Francisella tularensis using Mesoporous Silica Nanoparticle-Supported Lipid Bilayers

Marissa Anderson 1 2 Katharine Epler 2 3 David Padilla 4 Patrick Fleig 1 Jeffrey Brinker 2 5 Eric Carnes 1 Carlee Ashley 3

1Sandia National Laboratories Albuquerque USA2University of New Mexico Albuquerque USA3Sandia National Laboratories Albuquerque USA4University of New Mexico Albuquerque USA5Sandia National Laboratories Albuquerque USA

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4:00 AM - Y7
BREAK

4:30 AM - *Y7.06
Materials to Direct Human Pluripotent Stem Cell Differentiation

Laura Kiessling 1

1University of Wisconsin-Madison Madison USA

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5:00 AM - Y7.07
Processing and Production of Nanovesicle-Drug Conjugates as Novel Nanomedicines with Compressed Fluids

Jaume Veciana 1 2 Nora Ventosa 1 2 Santi Sala 2 1 Elisa Elizando 1 2 Ingrid Cabrera 1 2 Evelyn Moreno 1 2 Lidia Ferrer 1 2

1ICMAB BARCELONA Spain2CIBER-BBN BARCELONA Spain

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5:15 AM - Y7.08
Near Infrared Light-Triggered Degradation and Release from Polymeric Nanocapsules Using Upconverting Nanoparticles

Sha He 1 Mathieu L.- Viger 2 Noah J. J. Johnson 2 Carl-Johan Carling 2 Adah Almutairi 1 2 3

1University of California San Diego San Diego USA2University of California San Diego San Diego USA3University of California San Diego San Diego USA

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5:30 AM - Y7.09
Photodynamic Therapy of Alzheimer's Disease: Suppression of Beta-Amyloid Aggregation and Cell Cytotoxicity by Photo-Excited Porphyrin Delivery

Byung il Lee 1 Joon Seok Lee 2 Chan Beum Park 1

1Korea Advanced Institute of Science and Technology Daejeon Republic of Korea2Argonne National Laboratory Lemont USA

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Y8: Poster Session II
Session Chairs
Wednesday PM, April 23, 2014
Marriott Marquis, Yerba Buena Level, Salons 8-9

9:00 AM - Y8.01
Star-Branched PLA-PMPC Copolymer Micelles Prolong the Blood Circulation and Enhance Tumor-Targeted Delivery of Hydrophobic Drug In-Vivo

Lixia Long 1 Xiaomin Qian 1 Chaoyong Liu 1 Zhaoyang Li 1 Yu Ren 2 Zhenduo Cui 1 Xubo Yuan 1 Chunsheng Kang 3

1Tianjin University Tianjin China2Tianjin Medical University Tianjin China3Tianjin Medical University General Hospital Tianjin China

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9:00 AM - Y8.02
Photo-Controlled Intracellular Release of Anticancer Drugs from Gold Nanospheres by Non-Linear Excitation

Valerio Voliani 1 3 2 Giovanni Signore 3 Orazio Vittorio 4 5 Paolo Faraci 1 Stefano Luin 1 Julia Perez-Prieto 2 Fabio Beltram 1

1NEST - Scuola Normale Superiore Pisa Italy2Universidad de Valencia, Instituto de Ciencia Molecular, ICMol Valencia Spain3Center for Nanotechnology Innovation @NEST, Istituto Italiano di Tecnologia Pisa Italy4Children's Cancer Institute Australia, Lowy Cancer Research Centre, University of New South Wales Randwick Australia5Australian Centre for Nanomedicine, University of New South Wales Randwick Australia

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9:00 AM - Y8.04
Soft Robotic Micromold for the Generation of Non-Spherical Collagen Microparticles

Jun Kameoka 1 2

1Texas Aamp;M University College Station USA2Texas Aamp;M University College Station USA

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9:00 AM - Y8.06
The Effects of Varying Poly(ethylene glycol) Crosslinking Mechanism and Crosslinking Density on Protein Release

Soah Lee 1 Xinming Tong 2 Fan Yang 2 3

1Stanford University Stanford USA2Stanford University Stanford USA3Stanford University Stanford USA

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9:00 AM - Y8.07
Accelerating the Axonogenesis in Hippocampal Neurons Using Nanopillar Structures

Wenting Zhao 1 Kai Zhang 2 Wenjun Xie 2 Lindsey Hanson 2 Ziliang Lin 3 Yi Cui 1 4 Bianxiao Cui 2

1Stanford University Stanford USA2Stanford University Stanford USA3Stanford University Stanford USA4SLAC National Accelerator Laboratory Menlo Park USA

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9:00 AM - Y8.09
The Electrochemistry of In-Vitro Electrotaxis: How and What to Measure?

Maria Asplund 1 2

1Albert-Ludwigs Universitamp;#228;t Freiburg Germany2Albert-Ludwigs Universitamp;#228;t Freiburg Germany

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