Deducing Electric-Field Mediated Peptide Materials Design

Self-assembly of gene-encoded peptide motifs offers a bioinspired strategy for developing the design of functional nanomaterials.The current work illustrates contrasting effects of the electric field in the formation of peptide-based supramolecular materials. We have applied both atomistic and coarse-grained molecular dynamics simulations; our results highlight how the applied electric field can modulate the interaction between the hydrophobic and hydrophilic components of amphiphilic peptides, leading to the formation of dynamic soft materials.