Meetings & Events

 

2013 MRS Fall Meeting Logo2013 MRS Fall Meeting & Exhibit

December 1-6, 2013 | Boston
Meeting Chairs: Charles Black, Elisabetta Comini, Gitti Frey, Kristi Kiick, Loucas Tsakalakos

Symposium I : Multiscale Materials in the Study and Treatment of Cancer

2013-12-02   Show All Abstracts

Symposium Organizers

Shelly Peyton, University of Massachusetts
Nicole Moore, National Cancer Institute
Jess Snedeker, University and ETH Zurich
Courtney Williams, Regeneron Pharmaceuticals

Symposium Support

NCI
NSF
Regeneron Pharmaceuticals Inc.
Royal Society of Chemistry
I2: Quantitative Understanding and Treatment of Cancer
Session Chairs
Jess Snedeker
Courtney Williams
Monday PM, December 02, 2013
Sheraton, 2nd Floor, Back Bay B

2:30 AM - I2.01
Simultaneous Delivery of siRNA and Anticancer Drug Using Polymeric Nanoparticles

Xiaoyang Xu 1 2 Kun Xie 2 Xueqing Zhang 1 2 Eric Pridgen 2 Ga Young Park 2 Stephen Lippard 2 Robert Langer 2 Graham Walker 2 Omid Farokhzad 1

1Harvard Medical School Boston USA2Massachusetts Institute of Technology Boston USA

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2:45 AM - I2.02
Layer-by-Layer Functionalized Nanomedicine

Stephen Morton 1 2 Zhiyong Poon 2 Zhou Deng 2 Nisarg Shah 1 2 Michael Lee 2 3 Erik Dreaden 2 Mohiuddin Quadir 2 Kevin Shopsowitz 2 Michael Yaffe 2 3 Paula Hammond 1 2

1Massachusetts Institute of Technology Cambridge USA2Massachusetts Institute of Technology Cambridge USA3Massachusetts Institute of Technology Cambridge USA

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3:00 AM - I2.03
Orientation-Specific Attachment of Polymeric Microtubes on Cell Surfaces

Jonathan B Gilbert 1 Janice S O'Brien 2 Harini S Suresh 2 Robert E Cohen 1 Michael F Rubner 2

1Massachusetts Institute of Technology Cambridge USA2Massachusetts Institute of Technology Cambridge USA

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3:15 AM - I2.04
Optimized Protocol for the Use of Thermo-Sensitive Liposome in Tumor Therapeutics

Jae Min Cha 1 Eun-Jung Choi 1 Sang-Jun Park 1 Sun Min Park 1 Eun-Sung Park 1 Hyun Ryoung Kim 1

1Samsung Advanced Institute of Technology Yongin-Si, Gyeonggi-Do Republic of Korea

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3:30 AM - I2.05
pH-Responsive Expansile Nanoparticle Mediated Delivery of Paclitaxel to Peritoneal Carcinomatosis of Pancreatic Origin

Aaron Colby 1 Nelson Ruiz-Opazo 2 Glaiza A. Tan 2 Victoria Herrera 2 Mark W. Grinstaff 1

1Boston University Boston USA2Boston University School of Medicine Boston USA

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3:45 AM -
BREAK

4:15 AM - *I2.06
Gradient Hydrogel Platforms to Analyze Glioma Malignancy

Sara Pedron Haba 1 Eftalda Becka 2 Brendan Harley 1 2

1University of Illinois at Urbana-Champaign Urbana USA2University of Illinois at Urbana-Champaign Urbana USA

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4:45 AM - I2.07
Gold-Iron Oxide Nanoparticles for Photothermal Cancer Treatment

Georgios Sotiriou 1 2 Fabian Starsich 2 Sotiris E. Pratsinis 2

1Harvard University Boston USA2ETH Zurich Zurich Switzerland

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5:00 AM - I2.08
Nano Graphene Oxide - Hyaluronate Conjugate for Photo-Ablation Therapy of Melanoma Skin Cancer Using NIR Laser

Sei Kwang Hahn 1 Ho Sang Jung 1 Won Ho Kong 1 Min-Young Lee 1

1Pohang University of Science and Technology (POSTECH) Pohang Republic of Korea

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5:15 AM - I2.09
Magnetic Nanotubes for Cellular Signal Interrogation via Nanospearing

Zhen Yang 1 2 Dong Cai 1 Zhonghong Gao 2 Zhifeng Ren 1

1University of Houston Houston USA2Huazhong University of Science and Technology Wuhan China

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I3: Poster Session I: Cancer I
Session Chairs
Shelly Peyton
Nicole Moore
Courtney Williams
Jess Snedeker
Monday PM, December 02, 2013
Hynes, Level 1, Hall B

9:00 AM - I3.01
A Microfluidic Study of Nanoparticles in Simulated Blood Flows: Understanding the Effect of Margination

Erik Carboni 1 Grant Bouchillon 2 Leslie Shor 1 3 Suzy Torti 4 Anson Ma 5

1University of Connecticut Storrs USA2University of Connecticut Storrs USA3University of Connecticut Storrs USA4University of Connecticut Farmington USA5University of Connecticut Storrs USA

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9:00 AM - I3.02
Biocompatible Shaped Particles from Dried Multilayer Polymer Capsules

Veronika Kozlovskaya 1 Jun Chen 1 Mohammad Saeed 2 Eugenia Kharlampieva 1

1University of Alabama at Birmingham Birmingham USA2Southern Research Institute Birmingham USA

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9:00 AM - I3.03
Carborane-Kojic Acid Conjugate for Melanoma-Targeting Boron Neutron Capture Therapy

Riku Kawasaki 1 Koji Ono 2 Shin-ichiro Masunaga 2 Yosinori Sakurai 2 Mitsunori Kirihata 3 Takeshi Nagasaki 1

1Osaka City University Osaka Japan2Kyoto University Kumatori Japan3Osaka Prefecture University Sakai Japan

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9:00 AM - I3.05
Bioreducible Block Copolymers as the Carrier of Doxorubicin for Cancer Therapy

Hyewon Ko 1 Thavasyappan Thambi 2 Wooram Um 2 Jae Hyung Park 1 2

1Sungkyunkwan University Suwon Republic of Korea2Sungkyunkwan University Suwon Republic of Korea

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9:00 AM - I3.06
Leukemia Cells Detection Using Au-Nnoparticles/Jacalin Conjugates

Valeria Spolon Marangoni 1 Juliana Cancino 1 Valtencir Zucolotto 1

1University of Sao Paulo Samp;#227;o Carlos Brazil

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9:00 AM - I3.08
Gold Protruding Magnetic Nanoclusters for Magnetic Resonance Imaging Guided Photothermal Therapy

Aastha Kukreja 1 Eun-Kyung Lim 2 Jihye Choi 1 Eunji Jang 1 Hyun-Ouk Kim 1 Byunghoon Kang 1 Eun Bi Choi 1 Yong-Min Huh 2 Seungjoo Haam 1

1Yonsei University Seoul Republic of Korea2Yonsei University Seoul Republic of Korea

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9:00 AM - I3.09
In Vitro and In Vivo Delivery of Anticancer Therapeutics by Protein-Coated, pH-Responsive Mesoporous Silica Nanoparticles

Angela Hwang 1 Jie Lu 2 Fuyuhiko Tamanoi 2 Jeffrey Zink 1

1UCLA Los Angeles USA2UCLA Los Angeles USA

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9:00 AM - I3.10
NIR SERS Dots with Plasmonic Au/Ag Hollow-Shell Assemblies for In Vivo Multiplex Detection

Homan Kang 1 Sinyoung Jeong 2 Joonhyuk Yim 3 San Kyeong 3 Jin-Kyoung Yang 3 Jong-Ho Kim 5 Ho-Young Lee 4 Dae Hong Jeong 2 1 Yoon-Sik Lee 3 1

1Seoul National University Seoul Republic of Korea2Seoul National University Seoul Republic of Korea3Seoul National University Seoul Republic of Korea4Seoul National University Bundang Hospital Seongnam Republic of Korea5Hanyang University Ansan Republic of Korea

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9:00 AM - I3.11
Bioreducibly Crosslinked Hyaluronic Acid/siRNA Nanocomplexes for Systemic siRNA Delivery in Tumor Treatment

Roun Heo 1 Hong Yeol Yoon 2 3 Wooram Um 3 Kwangmeyung Kim 2 Ick Chan Kwon 2 Jae Hyung Park 1 3

1Sungkyunkwan University Suwon Republic of Korea2Korea Institute of Science and Technology Seoul Republic of Korea3Sungkyunkwan University Suwon Republic of Korea

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9:00 AM - I3.12
Naphthalocyanine Based Near-Infrared Photosensitizers for Photodynamic Therapy of Cancer

Wei Liu 1 Liqiang Luan 1 Lanlan Ding 1 Jiawei Shi 1

1Shandong University Jinan China

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9:00 AM - I3.13
Expansile Nanoparticle-Mediated Delivery Improves the Potency of Temozolomide against Glioblastoma Cells

Iriny Ekladious 1 Aaron H Colby 1 Glaiza A Tan 2 Nelson Ruiz-Opazo 2 Victoria Herrera 2 Mark W Grinstaff 1 3

1Boston University Boston USA2Boston University Boston USA3Boston University Boston USA

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9:00 AM - I3.15
LPEI-Coated Calcium Phosphate Nanoparticles for Long Chain microRNA Delivery

Hyosook Jung 1 Sung Young Park 2 Hyejung Mok 1

1Konkuk University Seoul Republic of Korea2Korea National University of Transportation Chungju Republic of Korea

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9:00 AM - I3.16
Detection of Melanoma Cells through Gold Nano-Needles

Jencilin Johnston 1 Thomas J Webster 1

1Northeastern University Boston USA

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9:00 AM - I3.17
Multifunctional Plasmonic Nanorattles for Spectrum-Guided Locoregional Therapy

Naveen Gandra 1 Christopher Portz 1 Srikanth Singamaneni 1

1Washington University in St. Louis St. Louis USA

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9:00 AM - I3.18
Hybrid Lipid-Polymer Nanoparticles for Delivery of Hydrophobic Drugs to Brain Tumors

Chung-Fan Kuo 1 Rajeshwer S. Jaswal 2 Sheereen Majd 1 3

1Pennsylvania State University University Park USA2Pennsylvania State University University Park USA3Pennsylvania State University University Park USA

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9:00 AM -
I3.14 TRANSFERRED TO I6.18

I1: Microenvironments and Nanoparticles to Quantify and Target Cancer
Session Chairs
Nicole Moore
Shelly Peyton
Monday AM, December 02, 2013
Sheraton, 2nd Floor, Back Bay B

10:00 AM - I1.02
Bioderived, Self-Loading, Aptamer-Virus-Porphyrin Nanoconstructs for Targeted Photodynamic Therapy

Magnus Bergkvist 1 Nuttawee Niamsiri 2 Brian Cohen 1

1University at Albany, SUNY Albany USA2Faculty of Science, Mahidol University Bangkok Thailand

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10:15 AM - I1.03
Combination Delivery of Chemotherapy Drugs and RNAi Using Layer-by-Layer Nanoparticles for Cancer Treatments

Jason Deng 1 Stephen Morton 1 Erik Dreaden 1 Paula Hammond 1

1MIT Cambridge USA

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10:30 AM - *I1.04
Bone Microenvironment Tissue Surrogates Engineered for Multiscale Reporting of Metastasized Breast Cancer Osteolytic Activity

Manu O Platt 1 2

1Georgia Institute of Technology Atlanta USA2Petit Institute for Bioengineering and Bioscience Atlanta USA

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11:00 AM -
BREAK

11:30 AM - I1.05
Detection and Treatment of Specific Cancer Cells Using Smart Nanoparticles

Si Yue Li 1 Min Wang 1

1The University of Hong Kong Hong Kong Hong Kong

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11:45 AM - I1.06
Preparation and Evaluation of 5-Fluorouracil Drug Delivery System with Calcium Carbonate Nanoparticles

Vijaya K Rangari 1 Diane Render 1 Temesgen Samuel 2 Madan Vig 3 Jay Ramapuram 4 Kasturi Pawar 4 Shaik Jeelani 1

1Tuskegee University Tuskegee USA2Tuskegee University Tuskegee USA3Auburn University Auburn USA4Tuskegee University Tuskegee USA

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12:00 PM - I1.07
Double-Targeted Theranostic Nanocarriers for PDT Therapy in Brain Tumors

Suraj Dixit 1 3 Yun Zhu 1 3 Alfred Moore 1 3 Malcolm Kenney 2 Ann-Marie Broome 1 3

1Medical University of South Carolina Charleston USA2Case Western Reserve University Cleveland USA3Medical University of South Carolina Charleston USA

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12:15 PM - I1.08
Imaging Of Genetically-Engineered Primary Human T-Cells with Multi-Modal Contrast Nanoparticles

Parijat Bhatnagar 1 Mian Alauddin 2 Payam Seifi 3 James A Bankson 4 Dickson Kirui 5 Helen Huls 6 Dean A Lee 6 7 Aydin Babakhani 3 Mauro Ferrari 5 King C Li 8 Laurence JN Cooper 6 7

1Baylor College of Medicine Houston USA2The University of Texas MD Anderson Cancer Center Houston USA3Rice University Houston USA4The University of Texas MD Anderson Cancer Center Houston USA5The Methodist Hospital Research Institute Houston USA6The University of Texas MD Anderson Cancer Center Houston USA7The University of Texas MD Anderson Cancer Center Houston USA8The Methodist Hospital Research Institute Houston USA

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2013-12-03   Show All Abstracts

Symposium Organizers

Shelly Peyton, University of Massachusetts
Nicole Moore, National Cancer Institute
Jess Snedeker, University and ETH Zurich
Courtney Williams, Regeneron Pharmaceuticals

Symposium Support

NCI
NSF
Regeneron Pharmaceuticals Inc.
Royal Society of Chemistry
I5: Materials Design to Understand and Treat Cancer
Session Chairs
Jess Snedeker
Shelly Peyton
Tuesday PM, December 03, 2013
Sheraton, 2nd Floor, Republic A

2:30 AM - I5.01
Magnetic Nanotechnology Platform for Protein Analysis of Circulating Microvesicles

Huilin Shao 1 Jaehoon Chung 1 Leonora Balaj 2 Alain Charest 3 Darell Bigner 4 Bob Carter 5 Fred Hochberg 6 Xandra Breakefield 2 Ralph Weissleder 1 Hakho Lee 1

1Massachusetts General Hospital Boston USA2Harvard Medical School Boston USA3Tufts University School of Medicine Boston USA4Duke University Medical Center Durham USA5UCSD School of Medicine San Diego USA6Massachusetts General Hospital Boston USA

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2:45 AM - I5.02
Microfluidic Fabrication of MR Visible Drug Eluting Magnetic Microspheres for Liver Tumors

Dong-Hyun Kim 1 2 Jeane Chen 1 Yang Guo 1 Zhuoli Zhang 1 Daniel Procissi 1 Reed A Omary 3 Andrew C Larson 1 2 4

1Northwestern Feinberg School of Medicine Chicago USA2Robert H. Lurie Comprehensive Cancer Center, Northwestern Memorial Hospital Chicago USA3Vanderbilt University Medical Center Nashville USA4Northwestern University Evanston USA

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3:00 AM - I5.03
Cell Membrane Model and In Vitro Assay for Toxicological Investigation

Juliana Cancino Bernardi 1 Paula Lins 1 Valeria Spolon Marangoni 1 Zucolotto Valtencir 1

1University of Sao Paulo Sao Carlos Brazil

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3:15 AM - *I5.04
Cell-Derived Materials: Mimicking Architectural and Oncogenic Influences of Natural Tumor Associated Extracellular Matrices

Edna Cukierman 1 Vivekanand Gupta 1 Janusz Franco-Barraza 1 Neelima Shah 1 Karthik Devarajan 3 Yan Zhou 3 Kathy C Cai 1 Andres J.P. Klein-Szanto 1 Robert G Uzzo 2

1Fox Chase Cancer Center (Temple Health) Philadelphia USA2Fox Chase Cancer Center (Temple Health) Philadelphia USA3Fox Chase Cancer Center (Temple Health) Philadelphia USA

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3:45 AM -
BREAK

4:15 AM - I5.05
Ultrabright Silica Nanoparticles for Detection of Cervical Cancer Cells

Shajesh Palantavida 1 Craig D. Woodworth 3 Igor Sokolov 1 2

1Tufts University Medford USA2Tufts University Medford USA3Clarkson University Potsdam USA

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4:30 AM - I5.06
Development and Optimization of Multimodal Near-IR Contrast Agents for Immune Cell Tracking

Pratixa P Joshi 1 Soon Joon Yoon 1 Stanislav Emelianov 1 2 Konstantin Sokolov 1 2

1University of Texas at Austin Austin USA2M.D. Anderson Cancer Center Houston USA

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4:45 AM - I5.07
Biomimetic Nanoparticles with Enzymatic Activity for Replacement Therapy of Sulfite Oxidase Deficiency

Ruben Ragg 1 Filipe Natalio 1 Steffen Lorenz 1 Susanne Strand 2 Dennis Strand 1 Wolfgang Tremel 2

1Johannes Gutenberg-Universitamp;#228;t Mainz Germany2Johannes Gutenberg-Universitamp;#228;t Mainz Germany

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5:00 AM - I5.08
Self-Assembled Camptothecin Prodrug for Treatment of Multidrug Resistant Cancer

Qiong Tang 1 Bin Cao 1 Gang Cheng 1

1University of Akron Akron USA

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I6: Poster Session II: Cancer II
Session Chairs
Shelly Peyton
Nicole Moore
Jess Snedeker
Courtney Williams
Tuesday PM, December 03, 2013
Hynes, Level 1, Hall B

9:00 AM - I6.02
MOF Nanospheres for Drug Delivery: Material Synthesis, Molecule Encapsulation, and Cellular Uptake

Jia Zhuang 1 Eranthie Weerapana 1 Chia-Kuang Tsung 1

1Boston College Chestnut Hill USA

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9:00 AM - I6.03
Theranostic Anticancer Agents Based on Internally Functionalized ORMOSIL Nanoparticles

Zhe Gao 1 Nathan I Walton 1 Ilya Zharov 1

1University of Utah Salt Lake City USA

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9:00 AM - I6.04
Effect of High Aspect Ratio Carbon Nanoparticles on Breast Cancer Cell Adhesion

Elizabeth M. Wailes 1 2 Elizabeth G. Graham 1 2 Nicole H. Levi-Polyachenko 1 2

1Wake Forest University Winston Salem USA2Wake Forest University Winston Salem USA

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9:00 AM - I6.05
Photo-Crosslinked Hyaluronic Acid Nanoparticles as the Robust Nanocarrier of the Anticancer Drug for Cancer Therapy

Hong Yeol Yoon 1 2 Wooram Um 1 Ki Young Choi 2 Ick Chan Kwon 2 3 Kuiwon Choi 2 Jae Hyung Park 1 Kwangmeyung Kim 2

1Sungkyunkwan University Suwon Republic of Korea2Korea Institute of Science and Technology Seoul Republic of Korea3Korea University Seoul Republic of Korea

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9:00 AM - I6.06
pH-Sensitive Hyaluronic Acid-Methotrexate Conjugates for the Treatment of Rheumatoid Arthritis

Jung Min Shin 1 Seol-hee Kim 2 Thavasyappan Thambi 3 Wooram Um 3 Jaehyung Park 1 4

1Sungkyunkwan University Suwon Republic of Korea2Sungkyunkwan University Suwon Republic of Korea3Sungkyunkwan University Suwon Republic of Korea4Sungkyunkwan University Suwon Republic of Korea

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9:00 AM - I6.07
Monitoring Controlled Release of Payload from Gold Nanocages Using Surface Enhanced Raman Scattering

Limei Tian 1 Naveen Gandra 1 Srikanth Singamaneni 1

1Washington University in St. Louis St. Louis USA

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9:00 AM - I6.08
Properties of Au-Mn Nanoparticles Synthesized by Pulsed Laser Ablation in Liquids

Daniel Guay 1 Teresa Simao 1 Gregory Goupil 1 Sebastien Garbarino 1 Marc-Andre Fortin 2 3 4

1Institut National de la Recherche Scientifique (INRS) Varennes Canada2Universitamp;#233; Laval Quamp;#233;bec Canada3Universitamp;#233; Laval Quamp;#233;bec Canada4Centre de Recherche du Centre Hospitalier Universitaire de Quamp;#233;bec (CRCHUQ) Quamp;#233;bec Canada

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9:00 AM - I6.11
Dual Surface-Functionalized Janus Nanocomposites of Polystyrene/Fe3O4@SiO2 for Simultaneous Tumor Cell Targeting and pH-Triggered Drug Release

Donglu Shi 1 3 Feng Wang 1 Giovanni Pauletti 2 Yilong Wang 3

1University of Cincinnati Cincinnati USA2University of Cincinnati Cincinnati USA3Tongji University School of Medicine Shanghai China

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9:00 AM - I6.14
Tunable Hydrogels to Understand the Microenvironmentrsquo;s Role in Regulating Breast Cancer Dormancy and Recurrence

Lisa Sawicki 1 April Kloxin 1

1University of Delaware Newark USA

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9:00 AM - I6.15
A New Possibility for Magnetic Nanoparticle Temperature Measurement

Daniel Reeves 1 John Weaver 1 2

1Dartmouth College Hanover USA2Geisel School of Medicine Hanover USA

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9:00 AM - I6.17
Development of Polyhydroxyalkanoate Nanaoparticles for Anti-Cancer Drug Delivers in Photodynamic Therapy

Nuttawee Niamsiri 1 Sasivimon Pramual 1 Apinya Asavanig 1 Panya Sunintaboon 2 Carl Batt 3 Magnus Bergkvist 4 Kriengsak Lirdprapamongkol 5 M.R. Jisnuson Svasti 5

1Faculty of Science, Mahidol University Bangkok Thailand2Faculty of Science, Mahidol University Bangkok Thailand3Cornell University Ithaca USA4College of Nanoscale Science and Engineering, University at Albany Albany USA5Chulabhorn Research Institute Bangkok Thailand

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9:00 AM - I6.18
Predicting Cell Transformation Using Mechanics and Metabolism

Chungchueh Chang 1 Kevin Pereira 2 Jin Guo 2 Vladimir Jurukovski 1 2 3 Miriam Rafailovich 1 Marcia Simon 2

1SUNY at Stony Brook Stony Brook USA2SUNY at Stony Brook Stony Brook USA3Suffolk coummnity College Brentwood USA

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9:00 AM - I6.19
Polyacrylate Nanoparticles Mediated Cytotoxic Process in Breast Cancer 4T1 Cell Line

Susan S Barros 1 Jaqueline R Silva 2 Ricardo B Azevedo 2 Claure N Lunardi 1 Anderson J Gomes 1

1University of Brasilia Brasilia Brazil2University of Brasilia Brasilia Brazil

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I4: Drug Delivery and Enhanced Targeting
Session Chairs
Courtney Williams
Nicole Moore
Tuesday AM, December 03, 2013
Sheraton, 2nd Floor, Back Bay B

9:30 AM - I4.01
Orientation and Density-Controlled Conjugation of Tandem Antibody to Fluorescent Carbon Nanotubes for Enhanced Effective Affinity and Selectivity to Target Biomolecules

Hye-In Kim 1 Dobin Hwang 1 Su-Ji Jeon 2 Jung-Hyun Park 2 Junho Chung 2 Jong-Ho Kim 1

1Hanyang University Ansan Republic of Korea2Seoul National University College of Medicine Seoul Republic of Korea

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9:45 AM - I4.02
Programmed Delivery of Drugs within Target Cells Using Aptamer-Polymer Hybrids

Seung Soo Oh 1 Bongjae F. Lee 1 2 Frank A. Leibfarth 2 3 Michael S. Eisenstein 1 4 Maxwell J. Robb 2 3 Nathaniel A. Lynd 2 Craig J. Hawker 1 2 3 H. Tom Soh 1 4

1University of California, Santa Barbara Santa Barbara USA2University of California, Santa Barbara Santa Barbara USA3University of California, Santa Barbara Santa Barbara USA4University of California, Santa Barbara Santa Barbara USA

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