The National Science Foundation (NSF) Division of Materials research in the Directorate for Mathematical and Physical Sciences (MPS) has developed a partnership with the Division of Cancer Biology (DCB) and the Center for Cancer Training (CCT) of the National Cancer Institute (NCI) at the National Institutes of Health (NIH). The aim of this collaboration is to inspire the Materials Science community to grow interest in working with cancer biologists to develop materials with new characteristics. In this process, cancer biologists would progress toward finding solutions to complex problems in cancer research. The partnership led to a series of Square Table workshops in 2021 and a Dear Colleague Letter to advance an emerging interdisciplinary field in which cancer can be used as a model to develop new living materials.
In continuation of this effort and to accelerate federal efforts to advance biotechnology and biomanufacturing toward innovative solutions in health, climate change, energy, food, agriculture, supply chain resilience, NSF and NCI will hold this outreach activity to engage with materials scientists during the 2024 MRS Fall Meeting.
The event is aimed at materials scientists who haven't previously collaborated with cancer researchers but are open to using cancer properties as a model for creating new materials for innovative applications. Additionally, it seeks to connect with materials researchers interested in advancing cancer research through the development of novel materials. The event will feature four talks by researchers who work on projects supported by NSF and NCI that will showcase the potential synergy at the intersection of materials science and cancer research. The session will also invite attendees to ask questions and participate in a panel discussion that will explore how new areas and recent advances in materials science could be applied to cancer research.
This event will communicate the needs and opportunities for materials researchers to get involved in developing a model for creating new materials to advance interdisciplinary materials research and technology to improve not only the fundamentals of materials research, but in the process develop new understanding and mechanisms of cancer biology.
Steven Becker
National Cancer Institute/National Institutes of Health, Moderator
Ming Guo
Massachusetts Institute of Technology, Panelist
Biomechanics of Cancer Invasion
Ming Guo is currently an associate professor in the Department of Mechanical Engineering at the Massachusetts Institute of Technology (MIT), and associated faculty in the MIT Physics of Living Systems Center and Center for Multi-Cellular Engineered Living Systems. Before joining MIT in 2015, Guo obtained his PhD degree in 2014 in applied physics and MS degree in 2012 in mechanical engineering at Harvard University, and BS degree in engineering mechanics at Tsinghua University. He has won numerous awards including the Alfred P, Sloan Fellow in Physics and International Union of Pure and Applied Physics (IUPAP) Young Scientist Prize in Biological Physics. Guo is an associate editor of the Journal of Biological Physics.
Roger Kamm
Massachusetts Institute of Technology, Panelist
A Decade of Bridging a Research Program Between NSF and NCI
Roger Kamm is the Cecil and Ida Green Distinguished Professor of Biological and Mechanical Engineering at the Massachusetts Institute of Technology (MIT). His research has focused on problems at the interface of biology and mechanics, formerly in cell and molecular mechanics, and in engineered living systems. Current interests include developing a microphysiological system (MPS) of healthy and diseased organ function with a focus on vascularization. Kamm is a recipient of the Lissner Medal, the Nerem Medal and the Shu Chien Award, and is a Fellow of the US National Academies of Medicine and Engineering. He is co-founder of AIM Biotech, a manufacturer of microfluidic systems for 3D culture.
Jin Montclare
New York University, Panelist
Engineering Exosome-Based Biomaterials as Living Materials
Jin Kim Montclare is a professor in the Department of Chemical and Biomolecular Engineering, Chemistry, Biomaterials and Radiology at New York University. She is performing groundbreaking research in engineering proteins to mimic nature and, in some cases, work better than nature. She exploits nature’s biosynthetic machinery and evolutionary mechanisms to design new artificial proteins. Her lab focuses on two research areas: (1) developing protein biomaterials and (2) engineering functional proteins/enzymes for particular substrates with the aim of targeting human disorders, drug delivery, tissue regeneration and the environment. Montclare leads the multidisciplinary Convergence of Innovation and Entrepreneurship (CIE) Institute and the Computationally Designed-Genetically Engineered Materials (CD-GEM). She has garnered several awards and honors including but not limited to the Air Force Office of Scientific Research Young Investigator Award, American Chemical Society (ACS) Women Chemists Committee Rising Star Award, American Institute for Medical and Biological Engineering (AIMBE) College of Fellows, the American Association for the Advancement of Science (AAAS) Leshner Fellowship on Human Augmentation, inducted into the National Academy of Inventors, and most recently the American Association of Colleges and Universities (AAC&U) Convergence Program Fellowship.
David Mooney
Harvard University, Panelist
Biological Inspiration for Tough Gels
David Mooney is the Pinkas Family Professor of Bioengineering in the Harvard School of Engineering and Applied Sciences, and a Core Faculty Member of the Wyss Institute. His laboratory designs biomaterials to promote regeneration and immunotherapy. He is a member of the National Academy of Engineering, the National Academy of Medicine, and the National Academy of Inventors. His inventions have been licensed by over 20 companies, leading to commercialized products. He has founded companies and is active on industrial scientific advisory boards.
Germano Iannacchione
National Science Foundation—Division of Materials Research, Speaker
Division Director, Division of Materials Research (DMR)
Directorate for Mathematical and Physical Sciences (MPS)
National Science Foundation
new.nsf.gov/staff/giannacc
Shadi Mamaghani
National Science Foundation—Division of Materials Research, Speaker