In Situ Characterization of Electrochemical Transistors for High-Performance Biosensing

Solid-liquid interfaces have garnered significant attention for applications in bioelectronics, electrochromics, energy storage/generation, neuromorphic computing, and thermoelectrics. These devices operate in electrolytes that render ions mobile in the film, making the coupling between electronic and ionic charges crucial. An example of such a device is the organic electrochemical transistor (OECT), a high-gain transducer commonly used to monitor bio-ionic signals. In this talk, I will demonstrate OECT-based protein sensors based on organic mixed conductors and discuss the importance of the semiconductor type used in the channel and device dimensions for high-performance biosensing, based on the results acquired through a combination of operando techniques. I will also introduce polymer design and processing approaches that endow organic bioelectronic devices with longer shelf life and operational stability.