Skin-Interfaced Wearable Biosensors based on Laser-Engraved Graphene

Laser-engraved graphene (LEG) has been applied increasingly in wearable and flexible electronics over the past decade owing to its unique physical and chemical properties. It has shown great promise in energy controls, chemical and physical sensing, and telemedicine. In this talk, I will introduce our efforts in developing LEG-based wearable biosensors for non-invasive molecular analysis. Such wearables can autonomously access body fluids (e.g., human sweat) across the activities and continuously measure a broad spectrum of analytes including metabolites, nutrients, hormones, proteins, and drugs. Laser engraving enables the manufacturing of high-performance nanomaterials-based biosensors at large scale and low cost. The clinical value of our LEG-based wearable systems is evaluated through various human trials toward precision nutrition, stress/mental health assessment, and chronic disease management (e.g., systemic inflammation monitoring). These wearable technologies could open the door to a wide range of personalized monitoring, diagnostic, and therapeutic applications.