Organic Bioelectronics Grown onto Cells and in the Brain

An array of different thiophene-based monomers and trimers has been synthesized that combines electronic, chemical, and pharmaceutical functions. These materials have been applied onto and into various cell and tissue systems to form seamless bioelectronics that is amalgamated with biology. Selectivity to specific biological components and structures enables us to form well-defined electroactive structures and devices that promise for radically new tools to record and stimulate biological functions, such as neuro-signaling. Our goal is to apply this new bioelectronic toolkit to different disease models, such as neurodegenerative diseases.