Biointegrated Living Electronics for Healthcare

The emerging field of living bioelectronics aims to seamlessly integrate electronic devices with biological tissues, offering transformative solutions in healthcare diagnostics and therapeutics. In this talk, I will begin by discussing our earlier efforts centered around engineered tissue-integrated bioelectronics and the construction of tissue-mimetic materials. Progressing from these foundational works, I will transition into our latest explorations that harness the synergy between biology and electronics to address intricate biomedical challenges. Specifically, we present the active biointegrated living electronics platform. This unique interface, integrating a bioelectronics framework with a bacteria-laden hydrogel composite, facilitates dynamic signal transduction between microbial and mammalian systems. This platform has demonstrated its potential by monitoring microbial interventions in several skin conditions. As we forge ahead, our focus will be on optimizing device longevity, enhancing efficiency, and unveiling novel therapeutic solutions.