April 22 - 26, 2024
Seattle, Washington
May 7 - 9, 2024 (Virtual)

Event Supporters

2024 MRS Spring Meeting
SB10.08.08

Tissue-Interfaced Electronics for Directing Biological Functions

When and Where

Apr 25, 2024
11:30am - 12:00pm
Room 429, Level 4, Summit

Presenter(s)

Co-Author(s)

Toshinori Fujie1

Tokyo Institute of Technology1

Abstract

Toshinori Fujie1

Tokyo Institute of Technology1
Integration of flexible electronics into the living system is expected for advancing medical diagnostics and therapeutics. Such devices should be seamlessly conformed to the physical and mechanical environment of living body, in which acquired biosignals are expected to be transmitted wirelessly to external device. In this regard, we envisage the development of tissue-interfaced electronics for wearable and implantable applications based on polymer nanosheet technology. The polymer nanosheet shows tens- to hundreds-of-nanometer thickness close to the scale of biomembranes, in which various types of polymers (e.g., biodegradable polymers, conductive polymers, and elastomers) are formed into the ultra-thin structure. Free-standing polymer nanosheets showed flexible and adhesive properties derived from their ultra-small flexural rigidity (&lt; 10<sup>-2</sup> nN m). In this talk, polymer nanosheet (or thin film)-based devices are introduced by combining polymer nanosheet and printing technologies with variety of unique inks. A microgravure coater was employed for the preparation of flexible substrates or electrodes, an inkjet printer allowed for the tailor-made design of multielectrode array, and a laser processing machine was used for making the microchannels for insulating the circuit. The ultra-conformable structure has been utilized as tissue-interfaced electronics to direct biological functions in the applications of healthcare and medicine, represented by the wirelessly-powered light emitting device for photodynamic cancer therapy, and the flexible, thin-film neural electrode for diagnosis and treatment of epileptic seizure.

Keywords

biomaterial | ink-jet printing | thin film

Symposium Organizers

Simone Fabiano, Linkoping University
Sahika Inal, King Abdullah University of Science and Technology
Naoji Matsuhisa, University of Tokyo
Sihong Wang, University of Chicago

Symposium Support

Bronze
IOP Publishing

Session Chairs

Shinya Wai
Cunjiang Yu

In this Session