Nickel-Based Metal-Organic Framework (NiMOF) Decorated Single-Walled Carbon Nanotube (SWCNT) Fiber Electrolyte-Gated Field-Effect Transistors for Glucose Sensors

In this study, we present a novel approach for glucose sensing using single-walled carbon nanotube (SWCNT) fibers coated with nickel metal-organic framework (NiMOF). The SWCNT fibers, characterized by sub-micron size graphene nanosheets and oxidative functional groups, provide an ideal substrate for the attachment of NiMOF molecules, enhancing the sensor’s performance. We demonstrate the fabrication and characterization of electrolyte-gated field-effect transistors (EGFETs) based on NiMOF-SWCNT fibers for glucose detection. Using NiMOF-SWCNT fiber electrolyte-gated field-effect transistors for glucose sensing offers several advantages. The transistor structure provides low operating voltage, local amplification, and a high signal-to-noise ratio, making it suitable for direct contact with skin, where sweat can serve as an electrolyte. SWCNT fibers, which can be woven into fabrics or flexible platforms, serves as the substrate for the sensor. The NiMOF acts as nanozyme for nonenzymatic glucose sensors, eliminating the need for complex enzyme immobilization process.