Gold Nanoparticles-Coated Microneedles Based Glucose Sensor for Diabetes Diagnosis

Recently, the number of people with diabetes has increased due to changes in diet and lifestyle. Since diabetes is associated with many complications, such as cardiovascular disease and kidney problems, it is important to diagnose it early and treat it appropriately. However, blood glucose testing involves inserting and testing a needle four or five times a day, causing pain and discomfort to the patient. To overcome this problem, the researchers adopted a method to detect glucose using microneedles. The microneedles were fabricated using PEGDA(Polyethylene glycol diacrylate), which is highly biocompatible, and Au was coated on the surface of the needle instead of glucose enzyme to provide high conductivity and ease of measurement in various environments.<br/>This research has the advantage that the microneedles can be easily mass-produced by photolithography, which is economical, and the microneedles can be made as long as desired, making them suitable for people of all ages and races.<br/>This technology is expected to contribute to the medical industry as it can effectively measure glucose without pain.