New Device Concepts in Bioelectrical Interfaces for Translational Applications

Advances in bioelectronic devices interfacing with biological tissues offer significant medical benefits, such as for inflammation and pain management. This presentation highlights several innovations from our laboratory, including the Active Biointegrated Living Electronics (ABLE) platform, which combines living bacteria with hydrogels and wearable electronics for real-time inflammation monitoring and treatment. Additionally, we have developed new bioelectrical systems, including microbial electroceuticals for disinfection, and drug-free alternatives for pain relief and inflammation management. Our novel approaches utilize advanced device designs to provide precise, scalable, and efficient treatments. In concluding my talk, I will discuss future directions for bioelectrical interfaces, focusing on scaling these innovations for broader clinical applications, and addressing challenges related to biocompatibility and long-term stability.