Microscale Optoelectronic Devices for Advanced Neural Interfaces

Bio-integrated high performance inorganic optoelectronic devices will provide new insights on interactions between light and bio-systems. Here we present unconventional strategies to design and fabricate microscale, thin-film optoelectronics devices including micro-LEDs and photodetectors that can be formed via epitaxial liftoff and transfer printing techniques. These microscale devices can be heterogeneously integrated on flexible and stretchable substrates and interact with biological systems for biomedical applications. In particular, we produce multifunctional neural probes that can be directly implanted into the deep brain of freely moving animals, modulating and detecting neural activities in vivo.