2020 MRS Spring Meeting

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Symposium S.SM01 : Organ-on-a-Chip—Toward Personalized Precision Medicine

Available on demand   Show All Abstracts

Symposium Organizers

Venkatesan Renugopalakrishnan, Boston Children's Hospital/Harvard University/Northeastern University
Nasim Annabi, University of California, Los Angeles
D. Sakthi Kumar, Toyo University
Dorian Liepmann, University of California, Berkeley

Symposium Support

Bronze
Alnylam Pharmaceuticals
MilliporeSigma
S.SM01.01: Point of Care Systems
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.01.02
Nonenzymatic Biosensor Based Lab-on-a-Chip Device for Multi Organ Functional Analysis

Satheesh Babu1

Amrita Vishwa Vidyapeetham1

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S.SM01.02: Organ on a Chip
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.02.02
In Vitro Modeling of Non-Alcoholic Fatty Liver Disease by Integrated Gut-Liver on a Chip

Jiandong Yang1,Yoshikazu Hirai1,Ken-ichiro Kamei1,Marika Trumm2,1,Toshiyuki Tsuchiya1,Osamu Tabata1

Kyoto University1,Heidelberg University2

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S.SM01.03: 2D Nanomaterials Platform
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.03.01
Low-Dimensional Nano-Carbons—Form Doped Graphene to 3D Hybrids and Biological Applications

Mauricio Terrones1

The Pennsylvania State University1

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S.SM01.04: Advancing Oligonucleotides Based Therapeutics; Challenges and Recent Advancements
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.04.10
Chemical Engineering of Therapeutic Oligonucleotides

Anastasia Khvorova1

University of Massachusetts Medical School1

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S.SM01.05: Molecular Imaging
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.05.01
Mechanobiological Markers for Cancer Metastasis

Dinesh Katti1,2,MD Molla1,Sumanta Kar1,2,Kalpana Katti1,2

North Dakota State University1,NDSU2

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S.SM01.06: Poster Session: Organ-on-a-Chip—Toward Personalized Precision Medicine
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.06.01
Boron-Doped Graphene, Wide Band Gap 2D Nano Material as an Emerging Biosensor Platform

Venkatesan Renugopalakrishnan13,14,David Bryce1,Cesar Leroy2,Abhirup Patra3,Chetan Panchal4,Mitesh Panchal5,Sivaram Arepalli6,Pulickel Ajayan6,Ramasamy Paulmurugan7,Muhammad Naradipa8,Angga Fauzi8,Andrivo Rusydi8,Dorian Liepmann9,Piran R. Kidambi10,Narayanan Tharangattu11,Subbiah Alwarappan12

University of Ottawa1,CNRS2,University of Pennsylvania3,University of Baroda4,Nirma University5,Rice University6,Stanford University School of Medicine7,National University of Singapore8,University of California Berkeley9,Vanderbilt University10,Tata Institute of Fundamental Research11,CSIR-Central Electrochemical Research Institute12,Boston Children’s Hospital, Harvard Medical School, Boston13,Northeastern University14

Show Abstract

Available on demand - S.SM01.06.02
Fabrication and Characterization of Semiconducting Fluorographene on Borosilicate Substrates

Vivekanandan Palaninathan8,Rahul Sharma1,Krishna Sahoo1,Teguh Asmara2,Stephen Grage3,Ruiqi Zhang4,Jianwei Sun4,Anne S Ulrich3,Andrivo Rusydi2,Subrahmanyam A5,Ramasamy Paulmurugan6,Dorian Liepmann7,Sakthi Kumar8,Venkatesan Renugopalakrishnan9,10,Narayanan Tharangattu1

Tata Institute of Fundamental Research1,Department of Physics, National University of Singapore, Singapore2,Karlsruhe Institute of Technology, Institute of Biological Interfaces (IBG-2)3,Tulane University4,Indian Institute of Technology5,Stanford University School of Medicine6,University of California Berkeley7,Toyo University8,Boston Children’s Hospital, Harvard Medical School9,Northeastern University10

Show Abstract

Available on demand - S.SM01.06.04
Well-Free Cell Agglomeration and Spheroid Forming Using Guided Surface Acoustic Waves through a Couplant Layer

Jiyang Mei1,Aditya Vasan1,Uri Magaram2,3,Kenjiro Takemura4,Sreekanth Chalasani2,James Friend1

University of California, San Diego1,Salk Institute for Biological Studies2,University of California San Diego3,Keio University4

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S.SM01.02: Organ on a Chip
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.02.03
Defective Organ-on-a-Chip Strategy

Xiuli Zhang1,Jiu Deng2,Yong Luo2,Bingcheng Lin3

Soochow University1,School of Chemical Engineering, Dalian University of Technology2,Dalian Institute of Chemical Physics, Chinese Academy of Sciences3

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S.SM01.03: 2D Nanomaterials Platform
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.03.03
Engineering Conductive and Adhesive Cardiopatches for Cardiac Tissue Regeneration

Nasim Annabi1,3,4,Brian Walker1,Roberto Portillo Lara2

University of California, Los Angeles1,Tecnologico de Monterrey2,Brigham and Women's Hospital3,California NanoSystems Institute4

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S.SM01.01: Point of Care Systems
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.01.04
Resonance Frequency Modulation for Rapid Point-of-Care Ebola Glycoprotein Diagnosis with a Graphene-Based Field-Effect Bio-Transistor

Junhong Chen1,2

The University of Chicago1,Argonne National Laboratory2

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S.SM01.04: Advancing Oligonucleotides Based Therapeutics; Challenges and Recent Advancements
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.04.11
mRNA Therapy for Inhererited Metabolic Diseases

Lisa Rice1

Moderna1

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S.SM01.05: Molecular Imaging
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.05.02
Development of Molecular Imaging Smart Probes Based Technologies for High-Resolution Images of Prostate Cancer in MRI

Jebasingh Bhagavathsingh1,Divya Rajendran1,Sundar Manoharan2,Jannet Vennila1,Nagabhushan Vellala3

Karunya Institute of Technology and Sciences1,Satyabama Institute of Science and Technology2,Microbiological Laboratory Research and Service P Ltd3

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S.SM01.03: 2D Nanomaterials Platform
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.03.05
Ion-Selective Graphene-Hexagonal Boron Nitride Heterostructures for Biosensing

Adarsh Radadia1,Nowzesh Hasan1

Louisiana Tech University1

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S.SM01.02: Organ on a Chip
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.02.04
A Human Kidney on a Chip Microphysiological System

Edward Kelly1,Jonathan Himmelfarb1

University of Washington1

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S.SM01.05: Molecular Imaging
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.05.03
Raman Spectroscopy Investigation of Metastatic Prostate Cancer

Jeon Woong Kang1,Ramachandra Dasari1,Peter So1,Sumanta Kar2,Kalpana Katti2,Dinesh Katti2,Ramasamy Paulmurugan3,Dorian Liepmann4,Venkatesan Renugopalakrishnan5

Massachusetts Institute of Technology1,North Dakota State University2,Stanford University3,University of California, Berkeley4,Northeastern University5

Show Abstract

S.SM01.01: Point of Care Systems
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.01.05
Nanostructured Metal Oxides-Based Biosensors for Oral Cancer Detection

Bansi Malhotra1

Delhi Technological University1

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S.SM01.03: 2D Nanomaterials Platform
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.03.06
Self-Renewing Neural Circuits in a Millimeter-Sized Invertebrate

Jacob Robinson1

Rice University1

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S.SM01.04: Advancing Oligonucleotides Based Therapeutics; Challenges and Recent Advancements
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.04.01
Re-engineering RNA Molecules into Therapeutic Agents—The Expanding Universe of Nucleic Acid Modifications

Martin Egli1

Vanderbilt University1

Show Abstract

S.SM01.02: Organ on a Chip
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.02.05
Human Organs Chips For Drug Discovery and Personalized Medicine

Rachelle Prantil-Baun1,Donald Ingber1,2

Harvard University1,Vascular Biology Program, Boston Children's Hospital and Harvard Medical School2

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S.SM01.05: Molecular Imaging
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.05.04
Image Guided Delivery of microRNAs by Polyfunctional Gold-Iron Oxide Nanoparticles as a Diagnostic Platform for Monitoring Therapeutic Response of GBM In Vivo

Ramasamy Paulmurugan1

Stanford University1

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S.SM01.01: Point of Care Systems
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.01.06
Selectively Placed Graphene-Based Microfluidic Device for Point-of-Care Device Application

Vivekanandan Palaninathan1,Tomofumi Ukai1,Yoshikata Nakajima2,Narayanan Tharangattu3,Subhabrata Das4,Stephen Grage5,Anne S Ulrich5,Pingzuo Li6,Subrahmanyam A7,Ramasamy Paulmurugan8,Dorian Liepmann9,Ponisseril Somasundaran10,Pulickel Ajayan11,Venkatesan Renugopalakrishnan12,6,Sakthi Kumar1

Toyo University1,Institute for NanoScience Design, Osaka University2,Tata Institute of Fundamental Research3,Langmuir Center of Colloids and Interfaces, Columbia University4,Karlsruhe Institute of Technology, Institute of Biological Interfaces (IBG-2)5,Boston Children’s Hospital, Harvard Medical School6,Indian Institute of Technology7,Cellular Pathway Imaging Laboratory (CPIL), Department of Radiology, Stanford University8,University of California Berkeley9,Columbia University10,Rice University11,Department of Chemistry, Northeastern University, Boston, MA 02115. USA.12

Show Abstract

S.SM01.03: 2D Nanomaterials Platform
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.03.07
2D Nanomaterials

Anand Puthirath1,Pulickel Ajayan1

Rice University1

Show Abstract

S.SM01.04: Advancing Oligonucleotides Based Therapeutics; Challenges and Recent Advancements
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.04.02
Delivery of RNAi Therapeutics—Tackling a Billion Years of Evolutionary Defenses with New Chemistry

Steven Dowdy1,Ian Huggins1

University of California, San Diego1

Show Abstract

S.SM01.02: Organ on a Chip
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.02.06
Engineering of Microfluidic Tumor On-Chip Models to Study Cancer Metastasis

Mehdi Nikkhah1

Arizona State University1

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S.SM01.05: Molecular Imaging
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.05.05
Emerging Clinical Applications of Cuttying Edge MRI

Mukesh Harisinghani1

Massachusetts General Hospital1

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S.SM01.01: Point of Care Systems
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.01.07
Biphasic Nanodot Zirconia Based Efficient Biosensor for Non-Invasive Oral Cancer Detection

Bansi Malhotra1,4,Suveen Kumar1,2,Venkatesan Renugopalakrishnan3

Delhi Technological University1,University of Delhi2,Harvard Medical School3,Northeastern University4

Show Abstract

S.SM01.04: Advancing Oligonucleotides Based Therapeutics; Challenges and Recent Advancements
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.04.04
A Traceless Linker for Aliphatic Amines that Rapidly and Quantitatively Fragments after Reduction

Niren Murthy1,2

University of California, Berkeley1,Innovative Genomics Institute2

Show Abstract

S.SM01.02: Organ on a Chip
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.02.07
Micro/Nano-Engineering Approach for Developing Advanced Microphysiological Systems

Ken-ichiro Kamei1

Kyoto University1

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S.SM01.05: Molecular Imaging
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.05.06
Osteogenesis Pathways and Dysregulation at Bone Site in Breast Cancer Bone Metastasis

Kalpana Katti1,2,Sumanta Kar1,2,Dinesh Katti1,2

North Dakota State University1,NDSU2

Show Abstract

S.SM01.01: Point of Care Systems
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.01.08
Drop-on-Demand Inkjet Bioprinting for Tissue Engineering

Sungjune Jung1

Pohang University of Science and Technology1

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S.SM01.04: Advancing Oligonucleotides Based Therapeutics; Challenges and Recent Advancements
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.04.12
Boosting Intracellular Delivery of Messenger RNA

Gaurav Sahay1

Oregon Health & Science University1

Show Abstract

S.SM01.02: Organ on a Chip
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.02.08
Construction And Application of a Multi-Organ Microfluidic Chip Mimicking the In Vivo Pathological Process of Lung Cancer Brain Metastasis

Qi Wang1

Dalian Medical University1

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S.SM01.05: Molecular Imaging
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.05.07
Spectral Changes in Primary and Secondary Bone Metastasis Site Prostate Cancer Tissues Evaluated by Raman Mapping

Jairam Eswara1,Sumanta Kar2,3,Kalpana Katti2,3,Jeon Woong Kang4,Ramachandra Dasari4,Peter So4,Ramasamy Paulmurugan5,Dorian Liepmann6,Venkatesan Renugopalakrishnan7,8,Dinesh Katti2,3

St. Elizabeth's Medical Center1,North Dakota State University2,Center for Engineered cancer Testbeds3,MIT4,Stanford University5,University of California, Berkeley6,Northeastern University7,Harvard University8

Show Abstract

S.SM01.02: Organ on a Chip
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.02.12
3D Printed Device Mimicking Hepatic Lobule-Like Flow Conditions for Toxicity Testing

Anil Kumar P R1,Shiny Velayudhan1,Roopesh R. Pai1,Vinod Kumar V1

Sree Chitra Tirunal Institute for Medical Sciences and Technology1

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S.SM01.04: Advancing Oligonucleotides Based Therapeutics; Challenges and Recent Advancements
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.04.06
Escaping from microRNA Biogenesis—A Crucial Factor for Designing Functional Antisense microRNAs for Therapy

Ramasamy Paulmurugan1,Venkatesan Renugopalakrishnan2,3

Stanford University School of Medicine1,Harvard Medical School2,Northeastern University3

Show Abstract

Available on demand - *S.SM01.04.08
CRISPR-Powered Transistors—Harnessing Biology as Technology

Kiana Aran1

Keck Graduate Institute1

Show Abstract

S.SM01.02: Organ on a Chip
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.02.14
Fabrication of a Physiologically Relevant and Novel Lung-on-a-Chip Device for the Study of Human Pulmonary Disease and Drug Toxicity

David Blake1,Marcus Williams1,Jeff Jessing1

Fort Lewis College1

Show Abstract

Available on demand - *S.SM01.02.16
Innovative Organ-on-a-Chip (OOC) Platform Combined 3D Bioprinting Technology for Highly Reliable Human Tissure Mimicry

Yimin Guan1

Shanghai Industrial Technology Research Institute1

Show Abstract

S.SM01.04: Advancing Oligonucleotides Based Therapeutics; Challenges and Recent Advancements
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.04.09
Sense Anti-Sense MicroRNA Duplex—A Label Free Raman Study as an Approach for Functional Evaluation of Anti-Sense miRNA for Cancer Therapy

Preetham Ravi1,Surya Singh2,Jeon Woong Kang3,Ramachandra Dasari3,Peter So3,Dinesh Katti1,Kalpana Katti1,Dorian Liepmann4,Jairam Eswara5,Venkatesan Renugopalakrishnan6,Ramasamy Paulmurugan2

NDSU1,Stanford University2,Massachusetts Institute of Technology3,University of California, Berkeley4,St. Elizabeth Medical Center5,Harvard Medical School6

Show Abstract

S.SM01.02: Organ on a Chip
Session Chairs
Available on demand
S-SM01

Available on demand - S.SM01.02.17
A Novel Micro-injection Droplet Microfluidic System for Studying Locomotive Behavior Responses to Cu2+ induced Neurotoxin in Individual C.elegans

Zongzheng Chen1,Xiuli Zhang2,Yong Luo3,Bingcheng Lin4

First Affiliated Hospital of Shenzhen University1,Soochow University2,Dalian University of Technology3,Chinese Academy of Sciences4

Show Abstract

S.SM01.04: Advancing Oligonucleotides Based Therapeutics; Challenges and Recent Advancements
Session Chairs
Available on demand
S-SM01

Available on demand - *S.SM01.04.14
Role of Protein Corona on Oligonucleotide Delivery and Transfection with Lipid Nanoparticles

Mansoor Amiji1

Northeastern University1

Show Abstract

Available on demand - *S.SM01.04.13
Intracellular Delivery of mRNA; Exploration of Delivery Materials for Next Generation Therapeutics

David Ulkoski1

AstraZeneca PLC1

Show Abstract

2020-11-29   Show All Abstracts
S.SM01.07: Live Programming Session
Session Chairs
Sunday AM, November 29, 2020
S.SM01

12:30 PM - S.SM01.07
Live Session TBD


Show Abstract

2020-11-30   Show All Abstracts

Symposium Organizers

Venkatesan Renugopalakrishnan, Boston Children's Hospital/Harvard University/Northeastern University
Nasim Annabi, University of California, Los Angeles
D. Sakthi Kumar, Toyo University
Dorian Liepmann, University of California, Berkeley

Symposium Support

Bronze
Alnylam Pharmaceuticals
MilliporeSigma
S.SM01.08: Live Keynote I: Oligonucleotide
Session Chairs
Venkata Krishnamurthy
Venkatesan Renugopalakrishnan
Monday PM, November 30, 2020
S.SM01

5:15 PM - *S.SM01.04.01
Re-engineering RNA Molecules into Therapeutic Agents—The Expanding Universe of Nucleic Acid Modifications

Martin Egli1

Vanderbilt University1

Show Abstract

5:45 PM - *S.SM01.04.02
Delivery of RNAi Therapeutics—Tackling a Billion Years of Evolutionary Defenses with New Chemistry

Steven Dowdy1,Ian Huggins1

University of California, San Diego1

Show Abstract

6:15 PM - *S.SM01.04.04
A Traceless Linker for Aliphatic Amines that Rapidly and Quantitatively Fragments after Reduction

Niren Murthy1,2

University of California, Berkeley1,Innovative Genomics Institute2

Show Abstract

6:45 PM - S.SM01.04.06
Escaping from microRNA Biogenesis—A Crucial Factor for Designing Functional Antisense microRNAs for Therapy

Ramasamy Paulmurugan1,Venkatesan Renugopalakrishnan2,3

Stanford University School of Medicine1,Harvard Medical School2,Northeastern University3

Show Abstract

2020-12-02   Show All Abstracts

Symposium Organizers

Venkatesan Renugopalakrishnan, Boston Children's Hospital/Harvard University/Northeastern University
Nasim Annabi, University of California, Los Angeles
D. Sakthi Kumar, Toyo University
Dorian Liepmann, University of California, Berkeley

Symposium Support

Bronze
Alnylam Pharmaceuticals
MilliporeSigma
S.SM01.09: Live Keynote II: Oligonucleotide
Session Chairs
Venkata Krishnamurthy
Venkatesan Renugopalakrishnan
Wednesday AM, December 02, 2020
S.SM01

8:00 AM - *S.SM01.04.10
Chemical Engineering of Therapeutic Oligonucleotides

Anastasia Khvorova1

University of Massachusetts Medical School1

Show Abstract

8:25 AM - *S.SM01.04.11
mRNA Therapy for Inhererited Metabolic Diseases

Lisa Rice1

Moderna1

Show Abstract

8:50 AM - *S.SM01.04.12
Boosting Intracellular Delivery of Messenger RNA

Gaurav Sahay1

Oregon Health & Science University1

Show Abstract

9:15 AM - *S.SM01.04.14
Role of Protein Corona on Oligonucleotide Delivery and Transfection with Lipid Nanoparticles

Mansoor Amiji1

Northeastern University1

Show Abstract

9:40 AM - *S.SM01.09.01
Intracellular Delivery of mRNA; Exploration of Delivery Materials for Next Generation Therapeutics

David Ulkoski1

AstraZeneca PLC1

Show Abstract

2020-12-03   Show All Abstracts

Symposium Organizers

Venkatesan Renugopalakrishnan, Boston Children's Hospital/Harvard University/Northeastern University
Nasim Annabi, University of California, Los Angeles
D. Sakthi Kumar, Toyo University
Dorian Liepmann, University of California, Berkeley

Symposium Support

Bronze
Alnylam Pharmaceuticals
MilliporeSigma
S.SM01.10: Live Keynote III: CRISPR Based Technologies
Session Chairs
Kiana Aran
Dorian Liepmann
Thursday AM, December 03, 2020
S.SM01

8:00 AM - *
CRISPR-Powered Transistors—Harnessing Biology as Technology

Kiana Aran1

Keck Graduate Institute1

Show Abstract

8:35 AM - S.SM01.10
Harnessing CRISPR Diversity for at-home COVID Testing, Jonathan Gootenberg and Omar Abudayaeh


Show Abstract

9:00 AM - S.SM01.10
CRISPRoff: Spatio-Temporal Control of CRISPR Editing, Jared Carolson-Stevermer


Show Abstract

9:20 AM - S.SM01.10
PIPR - Proteome Analysis of CRISPR Cells, Jens-Ole Bock


Show Abstract

9:40 AM - S.SM01.10
The CRISPR Platform for Diagnostics, Sarah Shapiro


Show Abstract

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