2018 MRS Fall Meeting Home

Symposium BM09—Bioinspired Macromolecular Assembly and Inorganic Crystallization—From Tissue Scaffolds to Nanostructured Materials

Living organisms produce a wide variety of complex, nano-, micro-, and macroscale structured functional materials at high yields in an energy-efficient and highly reproducible manner, all under rather mild aqueous synthetic conditions. Throughout these processes, the high information content of specialized biomacromolecules, such as proteins, peptides and carbohydrates, enables 1) hierarchical organization to assemble scaffold materials and execute high-level functions; and 2) precise control over inorganic crystal nucleation, growth kinetics, phase and morphology, ultimately giving rise to biominerals with versatile functions. Inspired by nature, significant efforts been made towards developing the ability to mimic in vivo functions of these biomacromolecules by using engineered proteins, peptides, DNA, sequence-defined synthetic molecules (e.g. peptoids) and other biomimetic polymers. These efforts address one of the grand challenges of materials science—to design and synthesize functional materials that rival those found in biology.

This symposium will highlight recent developments in exploiting (bio)macromolecules 1) for self-assembly of soft matter with hierarchical structures, and 2) for controlling inorganic (nano)crystal nucleation and growth and assembly of inorganic (nano)crystals into superstructures. It will also address 3) the most recent insights obtained in the principles underlying (bio)macromolecular self-assembly, bio-controlled crystal formation and biomineralization (including using in situ molecular imaging and computational tools).

Topics will include:

  • Biomimetic formation of inorganic (nano)crystals (e.g. composite crystals, metal oxides and plasmonic nanoparticles)
  • Biomineralization
  • In situ characterization of bio-inspired assembly and bio-controlled crystal formation
  • Theory driven design of (bio)macromolecules for self-assembly and for controlling inorganic crystal formation
  • Hierarchical assembly of proteins, peptides, DNAs, peptoids and biomimetic polymers into nanostructured materials, including biomimetic membranes, nanotubes and hydrogels

Invited Speakers:

  • Vincent Conticello (Emory University, USA)
  • Baoquan Ding (National Center for NanoScience and Technology, China)
  • Alexander van Driessche (Université Grenoble Alpes, France)
  • John Evans (New York University, USA)
  • Fabrizio Gelain (Center for Nanomedicine and Tissue Engineering, Ospedale Niguarda Cà Granda, Italy)
  • Yu Huang (University of California, Los Angeles, USA)
  • Takashi Kato (University of Tokyo, Japan)
  • Marc Knecht (University of Miami, USA)
  • Thom LaBean (North Carolina State University, USA)
  • Robert Latour (Clemson University, USA)
  • Xiang Yang Liu (National University of Singapore, Singapore)
  • Fiona Meldrum (University of Leeds, United Kingdom)
  • Chad Mirkin (Northwestern University, USA)
  • Rajesh Naik (Air Force Research Laboratory, USA)
  • Carole Perry (Nottingham Trent University, United Kingdom)
  • Darrin Pochan (University of Delaware, USA)
  • Meital Reches (Hebrew University of Jerusalem, Israel)
  • Nathaniel Rosi (University of Pittsburgh, USA)
  • Mike Sleutel (Vrije Universiteit Brussel, Belgium)
  • Uwe Sleytr (University of Natural Resources and Life Sciences, Vienna, Austria)
  • Samuel Stupp (Northwestern University, USA)
  • Rein Ulijn (Hunter College City University of New York, USA)
  • Jim De Yoreo (Pacific Northwest National Laboratory, USA)
  • Ron Zuckermann (Lawrence Berkeley National Laboratory, USA)

Symposium Organizers

Chun-Long Chen
Pacific Northwest National Laboratory
Physical Sciences Division

Nico Sommerdijk
Eindhoven University of Technology
Department of Chemical Engineering and Chemistry

Tiffany Walsh
Deakin University
Institute for Frontier Materials

Shuguang Zhang
Massachusetts Institute of Technology
Center for Biomedical Engineering

Keywords for Abstract Submission

bio-inspired crystallization, macromolecular assembly, nanoparticle assembly, nanostructured materials, sequence-defined molecules

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