Symposium Q: Functional and Responsive Materials Exploiting Peptide and Protein Self-Assembly

Functional and Responsive Materials Exploiting Peptide and Protein Self-Assembly

Nature has evolved a variety of creative approaches to many aspects of materials synthesis and microstructural control. One such approach is self assembly, which represents a simple and efficient route to the construction of large, complex structures. This phenomenon is also a key process in all living organisms where many of the building blocks exhibit a hierarchy of structures that are critical to their functions. One area that is currently receiving attention is nanostructured and self-assembling biomaterials. In particular, the self assembly of proteins, peptides, and polypeptides, as well as peptide/protein-polymer conjugates, has been the focus of a significant body of work in recent years by a number of groups across the world. Significant progress has been made toward understanding the mechanism and driving forces behind the self assembly of these systems. This has led to the design of a new generation of functional and responsive materials for a diverse range of applications, such as tissue engineering, drug delivery, biosensing, microelectronics, templating, and energy harvesting.

This interdisciplinary symposium will bring together those working the field of materials design for specific applications exploiting the self-assembling properties of proteins, peptides, polypeptides, and protein/peptide/polymer hybrids.

Session topics will include:

  • Design, synthesis, and characterization of protein- and peptide-polymer conjugate-based materials
  • Design of hydride organic-peptide and/or protein-hybrid materials (including templating of functional materials and assembly of inorganic particles)
  • Designing 3-D functional structures exploiting the self-assembly of proteins, peptides, and their polymer conjugates (including hydrogels and organogels)
  • Designing 1-D nanostructured functional materials using self-assembling proteins, peptides, and their conjugates (including nanowire and nanotubes)
  • 2-D templated protein, peptide, and their conjugate self-assembly (including membranes, sheet, surface templating, and self-assembly at interfaces)
  • Exploiting protein, peptide, and their conjugate self-assembly for designing stimuli-responsive materials
  • Controlling biological interactions using protein, peptide, and their conjugate -based self-assembled materials (including controlling cell behavior and protein adhesion, triggering controlled immune responses)
  • Protein, peptide, and their conjugate-based hydrogels as scaffolds for tissue-engineering applications
  • Protein, peptide, and their polymer conjugate-based functional materials for biosensing, energy harvesting, and electronic applications
  • Protein, peptide, and their polymer conjugate-based materials for controlled and targeted drug delivery

Invited Speakers Include:

D. Adams (Liverpool Univ., United Kingdom), J. D. Hartgerink (Rice Univ.), S. Heilshorn (Stanford Univ.), H.-A. Klok (EPFL, Switzerland), H. Matsui (Hunter College), R. Mezzenga (ETH, Switzerland), A. F. Miller (Univ. of Manchester, United Kingdom), B. D. Olsen (Massachusetts Inst. of Technology), Jeffery G. Saven (Univ. of Pennsylvania), J. C. M. van Hest (Radboud Univ. Nijmegen, Netherlands), B. Xu (Brandeis Univ.).

Symposium Organizers

Alberto Saiani
University of Manchester
School of Materials
Grosvenor St., Manchester M1 7HS, United Kingdom
Tel 44-161-306-5981
Fax 44-161-306-3586
a.saiani@manchester.ac.uk

Joel Collier
University of Chicago
Division of Biological Sciences
5841 S. Maryland Ave., Chicago, IL 60637
Tel 773-834-4161
Fax 773-834-4546
jcollier@surgery.bsd.uchicago.edu

William Murphy
University of Wisconsin-Madison
Dept. of Biomedical Engineering and Pharmacology
1550 Engineering Dr., Madison, WI 53706
Tel 608-262-2224
Fax 608-265-9239
wlmurphy@wisc.edu

Laurent Jeannin
Peptisyntha SA (Solvay Group)
Advanced Peptide Biomaterials
310 rue de Ransbeek, B-1120 Brussels, Belgium
Tel 32-2-264-2006
laurent.jeannin@solvay.com

Darrin Pochan
University of Delaware
College of Engineering
201 DuPont Hall, Newark, DE 19716-1501
Tel 302-831-3569
Fax 302-831-4545
pochan@udel.edu 

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